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Rare and Common Variants in GALNT3 May Affect Bone Mass Independently of Phosphate Metabolism.
Hassan N, Gregson CL, Tang H, van der Kamp M, Leo P, McInerney-Leo AM, Zheng J, Brandi ML, Tang JCY, Fraser W, Stone MD, Grundberg E; Anglo-Australasian Genetics Consortium; Brown MA, Duncan EL, Tobias JH. Hassan N, et al. Among authors: zheng j. J Bone Miner Res. 2023 May;38(5):678-691. doi: 10.1002/jbmr.4795. Epub 2023 Mar 13. J Bone Miner Res. 2023. PMID: 36824040 Free PMC article.
Epigenome-wide Association of DNA Methylation in Whole Blood With Bone Mineral Density.
Morris JA, Tsai PC, Joehanes R, Zheng J, Trajanoska K, Soerensen M, Forgetta V, Castillo-Fernandez JE, Frost M, Spector TD, Christensen K, Christiansen L, Rivadeneira F, Tobias JH, Evans DM, Kiel DP, Hsu YH, Richards JB, Bell JT. Morris JA, et al. Among authors: zheng j. J Bone Miner Res. 2017 Aug;32(8):1644-1650. doi: 10.1002/jbmr.3148. Epub 2017 May 8. J Bone Miner Res. 2017. PMID: 28394087 Free PMC article. Clinical Trial.
Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis.
Kemp JP, Morris JA, Medina-Gomez C, Forgetta V, Warrington NM, Youlten SE, Zheng J, Gregson CL, Grundberg E, Trajanoska K, Logan JG, Pollard AS, Sparkes PC, Ghirardello EJ, Allen R, Leitch VD, Butterfield NC, Komla-Ebri D, Adoum AT, Curry KF, White JK, Kussy F, Greenlaw KM, Xu C, Harvey NC, Cooper C, Adams DJ, Greenwood CMT, Maurano MT, Kaptoge S, Rivadeneira F, Tobias JH, Croucher PI, Ackert-Bicknell CL, Bassett JHD, Williams GR, Richards JB, Evans DM. Kemp JP, et al. Among authors: zheng j. Nat Genet. 2017 Oct;49(10):1468-1475. doi: 10.1038/ng.3949. Epub 2017 Sep 4. Nat Genet. 2017. PMID: 28869591 Free PMC article.
Mendelian Randomization Analysis Reveals a Causal Influence of Circulating Sclerostin Levels on Bone Mineral Density and Fractures.
Zheng J, Maerz W, Gergei I, Kleber M, Drechsler C, Wanner C, Brandenburg V, Reppe S, Gautvik KM, Medina-Gomez C, Shevroja E, Gilly A, Park YC, Dedoussis G, Zeggini E, Lorentzon M, Henning P, Lerner UH, Nilsson KH, Movérare-Skrtic S, Baird D, Elsworth B, Falk L, Groom A, Capellini TD, Grundberg E, Nethander M, Ohlsson C, Davey Smith G, Tobias JH. Zheng J, et al. J Bone Miner Res. 2019 Oct;34(10):1824-1836. doi: 10.1002/jbmr.3803. Epub 2019 Aug 2. J Bone Miner Res. 2019. PMID: 31170332 Free PMC article.
GWAS meta-analysis followed by Mendelian randomization revealed potential control mechanisms for circulating α-Klotho levels.
Gergei I, Zheng J, Andlauer TFM, Brandenburg V, Mirza-Schreiber N, Müller-Myhsok B, Krämer BK, Richard D, Falk L, Movérare-Skrtic S, Ohlsson C, Davey Smith G, März W, Voelkl J, Tobias JH. Gergei I, et al. Among authors: zheng j. Hum Mol Genet. 2022 Mar 3;31(5):792-802. doi: 10.1093/hmg/ddab263. Hum Mol Genet. 2022. PMID: 34542150 Free PMC article.
Evaluation of the Effect of Sodium-Glucose Cotransporter 2 Inhibition on Fracture Risk: Evidence From Mendelian Randomization and Genetic Association Study.
Dai H, Zheng L, Zhu Z, Geng X, Hou T, Wang Q, Zhu Y, Lin H, Wang S, Zheng R, Zhao Z, Li M, Lu J, Xu Y, Wang T, Liu J, Ning G, Wang W, Bi Y, Zheng J, Xu M. Dai H, et al. Among authors: zheng r, zheng j, zheng l. J Bone Miner Res. 2023 Nov;38(11):1645-1653. doi: 10.1002/jbmr.4880. Epub 2023 Jul 27. J Bone Miner Res. 2023. PMID: 37436694 Free article.
Large-scale circulating proteome association study (CPAS) meta-analysis identifies circulating proteins and pathways predicting incident hip fractures.
Austin TR, Fink HA, Jalal DI, Törnqvist AE, Buzkova P, Barzilay JI, Lu T, Carbone L, Gabrielsen ME, Grahnemo L, Hveem K, Jonasson C, Kizer JR, Langhammer A, Mukamal KJ, Gerszten RE, Nethander M, Psaty BM, Robbins JA, Sun YV, Skogholt AH, Åsvold BO, Valderrabano RJ, Zheng J, Richards JB, Coward E, Ohlsson C. Austin TR, et al. Among authors: zheng j. J Bone Miner Res. 2024 Mar 22;39(2):139-149. doi: 10.1093/jbmr/zjad011. J Bone Miner Res. 2024. PMID: 38477735
Roles of gut microbiota in atrial fibrillation: insights from Mendelian randomization analysis and genetic data from over 430,000 cohort study participants.
Dai H, Hou T, Wang Q, Hou Y, Zhu Z, Zhu Y, Zhao Z, Li M, Lin H, Wang S, Zheng R, Xu Y, Lu J, Wang T, Ning G, Wang W, Zheng J, Bi Y, Xu M. Dai H, et al. Among authors: zheng r, zheng j. Cardiovasc Diabetol. 2023 Nov 8;22(1):306. doi: 10.1186/s12933-023-02045-6. Cardiovasc Diabetol. 2023. PMID: 37940997 Free PMC article.
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