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Sustained therapeutic benefits by transient reduction of TDP-43 using ENA-modified antisense oligonucleotides in ALS/FTD mice.
Takeuchi T, Maeta K, Ding X, Oe Y, Takeda A, Inoue M, Nagano S, Fujihara T, Matsuda S, Ishigaki S, Sahashi K, Minakawa EN, Mochizuki H, Neya M, Sobue G, Nagai Y. Takeuchi T, et al. Mol Ther Nucleic Acids. 2023 Jan 16;31:353-366. doi: 10.1016/j.omtn.2023.01.006. eCollection 2023 Mar 14. Mol Ther Nucleic Acids. 2023. PMID: 36817728 Free PMC article.
Phosphatidylinositol-3,4,5-trisphosphate interacts with alpha-synuclein and initiates its aggregation and formation of Parkinson's disease-related fibril polymorphism.
Choong CJ, Aguirre C, Kakuda K, Beck G, Nakanishi H, Kimura Y, Shimma S, Nabekura K, Hideshima M, Doi J, Yamaguchi K, Nakajima K, Wadayama T, Hayakawa H, Baba K, Ogawa K, Takeuchi T, Badawy SMM, Murayama S, Nagano S, Goto Y, Miyanoiri Y, Nagai Y, Mochizuki H, Ikenaka K. Choong CJ, et al. Among authors: takeuchi t. Acta Neuropathol. 2023 May;145(5):573-595. doi: 10.1007/s00401-023-02555-3. Epub 2023 Mar 20. Acta Neuropathol. 2023. PMID: 36939875 Free PMC article.
FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in C9orf72-linked ALS/FTD.
Fujino Y, Ueyama M, Ishiguro T, Ozawa D, Ito H, Sugiki T, Murata A, Ishiguro A, Gendron T, Mori K, Tokuda E, Taminato T, Konno T, Koyama A, Kawabe Y, Takeuchi T, Furukawa Y, Fujiwara T, Ikeda M, Mizuno T, Mochizuki H, Mizusawa H, Wada K, Ishikawa K, Onodera O, Nakatani K, Petrucelli L, Taguchi H, Nagai Y. Fujino Y, et al. Among authors: takeuchi t. Elife. 2023 Jul 18;12:RP84338. doi: 10.7554/eLife.84338. Elife. 2023. PMID: 37461319 Free PMC article.
CANVAS-related RFC1 mutations in patients with immune-mediated neuropathy.
Hirano M, Kuwahara M, Yamagishi Y, Samukawa M, Fujii K, Yamashita S, Ando M, Oka N, Nagano M, Matsui T, Takeuchi T, Saigoh K, Kusunoki S, Takashima H, Nagai Y. Hirano M, et al. Among authors: takeuchi t. Sci Rep. 2023 Oct 18;13(1):17801. doi: 10.1038/s41598-023-45011-8. Sci Rep. 2023. PMID: 37853169 Free PMC article.
Discrepancy in the Location of Prostate Cancer Indicated on Biparametric Magnetic Resonance Imaging and Pathologically Diagnosed Using Surgical Specimens.
Tomioka M, Nakane K, Kawase M, Iinuma K, Kato D, Kawase K, Taniguchi T, Tobisawa Y, Sugino F, Kaga T, Kato H, Matsuo M, Kito Y, Saigo C, Suzui N, Ito T, Miyazaki T, Takeuchi T, Koie T. Tomioka M, et al. Among authors: takeuchi t. Curr Oncol. 2024 May 16;31(5):2846-2855. doi: 10.3390/curroncol31050216. Curr Oncol. 2024. PMID: 38785497
Integrated safety analysis of filgotinib in patients with moderate-to-severe rheumatoid arthritis over a treatment duration of up to 8.3 years.
Burmester GR, Gottenberg JE, Caporali R, Winthrop KL, Tanaka Y, Ekoka Omoruyi EV, Rajendran V, Van Hoek P, Van Beneden K, Takeuchi T, Westhovens R, Aletaha D. Burmester GR, et al. Among authors: takeuchi t. Ann Rheum Dis. 2024 May 23:ard-2024-225759. doi: 10.1136/ard-2024-225759. Online ahead of print. Ann Rheum Dis. 2024. PMID: 38782549
Widespread use of proton pump inhibitors or potassium-competitive acid blocker has changed the status of gastrointestinal bleeding in patients with ischemic heart disease: real-world data from high volume centers.
Sasaki S, Ota K, Sanomura M, Mori Y, Tanaka H, Hakoda A, Sugawara N, Iwatsubo T, Hirata Y, Kakimoto K, Morita H, Nagamatsu W, Hoshiga M, Takeuchi T, Higuchi K, Nishikawa H. Sasaki S, et al. Among authors: takeuchi t. BMC Gastroenterol. 2024 May 21;24(1):177. doi: 10.1186/s12876-024-03269-w. BMC Gastroenterol. 2024. PMID: 38773435 Free PMC article.
5,611 results