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CYP1B1-derived epoxides modulate the TRPA1 channel in chronic pain.
Sun L, Zhang J, Niu C, Deering-Rice CE, Hughen RW, Lamb JG, Rose K, Chase KM, Almestica-Roberts M, Walter M, Schmidt EW, Light AR, Olivera BM, Reilly CA. Sun L, et al. Among authors: hughen rw. Acta Pharm Sin B. 2023 Jan;13(1):68-81. doi: 10.1016/j.apsb.2022.09.007. Epub 2022 Sep 14. Acta Pharm Sin B. 2023. PMID: 36815047 Free PMC article.
Electrophilic components of diesel exhaust particles (DEP) activate transient receptor potential ankyrin-1 (TRPA1): a probable mechanism of acute pulmonary toxicity for DEP.
Deering-Rice CE, Romero EG, Shapiro D, Hughen RW, Light AR, Yost GS, Veranth JM, Reilly CA. Deering-Rice CE, et al. Among authors: hughen rw. Chem Res Toxicol. 2011 Jun 20;24(6):950-9. doi: 10.1021/tx200123z. Epub 2011 May 25. Chem Res Toxicol. 2011. PMID: 21591660 Free PMC article.
Neuroactive Type-A γ-Aminobutyric Acid Receptor Allosteric Modulator Steroids from the Hypobranchial Gland of Marine Mollusk, Conus geographus.
Niu C, Leavitt LS, Lin Z, Paguigan ND, Sun L, Zhang J, Torres JP, Raghuraman S, Chase K, Cadeddu R, Karthikeyan M, Bortolato M, Reilly CA, Hughen RW, Light AR, Olivera BM, Schmidt EW. Niu C, et al. Among authors: hughen rw. J Med Chem. 2021 May 27;64(10):7033-7043. doi: 10.1021/acs.jmedchem.1c00562. Epub 2021 May 5. J Med Chem. 2021. PMID: 33949869
Nicotinic Acetylcholine Receptor Partial Antagonist Polyamides from Tunicates and Their Predatory Sea Slugs.
Paguigan ND, Tun JO, Leavitt LS, Lin Z, Chase K, Dowell C, Deering-Rice CE, Lim AL, Karthikeyan M, Hughen RW, Zhang J, Peterson RT, Reilly CA, Light AR, Raghuraman S, McIntosh JM, Olivera BM, Schmidt EW. Paguigan ND, et al. Among authors: hughen rw. ACS Chem Neurosci. 2021 Jul 21;12(14):2693-2704. doi: 10.1021/acschemneuro.1c00345. Epub 2021 Jul 2. ACS Chem Neurosci. 2021. PMID: 34213884 Free PMC article.
Microhabitats within venomous cone snails contain diverse actinobacteria.
Peraud O, Biggs JS, Hughen RW, Light AR, Concepcion GP, Olivera BM, Schmidt EW. Peraud O, et al. Among authors: hughen rw. Appl Environ Microbiol. 2009 Nov;75(21):6820-6. doi: 10.1128/AEM.01238-09. Epub 2009 Sep 11. Appl Environ Microbiol. 2009. PMID: 19749071 Free PMC article.
29 results