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CHD4 and SMYD1 repress common transcriptional programs in the developing heart.
Shi W, Wasson LK, Dorr KM, Robbe ZL, Wilczewski CM, Hepperla AJ, Davis IJ, Seidman CE, Seidman JG, Conlon FL. Shi W, et al. Among authors: wasson lk. Development. 2024 Apr 15;151(8):dev202505. doi: 10.1242/dev.202505. Epub 2024 May 3. Development. 2024. PMID: 38619323 Free PMC article.
The H2Bub1-deposition complex is required for human and mouse cardiogenesis.
Barish S, Berg K, Drozd J, Berglund-Brown I, Khizir L, Wasson LK, Seidman CE, Seidman JG, Chen S, Brueckner M. Barish S, et al. Among authors: wasson lk. Development. 2023 Dec 1;150(23):dev201899. doi: 10.1242/dev.201899. Epub 2023 Dec 1. Development. 2023. PMID: 38038666 Free PMC article.
Cardiomyocyte infection by Trypanosoma cruzi promotes innate immune response and glycolysis activation.
Venturini G, Alvim JM, Padilha K, Toepfer CN, Gorham JM, Wasson LK, Biagi D, Schenkman S, Carvalho VM, Salgueiro JS, Cardozo KHM, Krieger JE, Pereira AC, Seidman JG, Seidman CE. Venturini G, et al. Among authors: wasson lk. Front Cell Infect Microbiol. 2023 Feb 6;13:1098457. doi: 10.3389/fcimb.2023.1098457. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 36814444 Free PMC article.
Cardiac proteomics reveals sex chromosome-dependent differences between males and females that arise prior to gonad formation.
Shi W, Sheng X, Dorr KM, Hutton JE, Emerson JI, Davies HA, Andrade TD, Wasson LK, Greco TM, Hashimoto Y, Federspiel JD, Robbe ZL, Chen X, Arnold AP, Cristea IM, Conlon FL. Shi W, et al. Among authors: wasson lk. Dev Cell. 2021 Nov 8;56(21):3019-3034.e7. doi: 10.1016/j.devcel.2021.09.022. Epub 2021 Oct 15. Dev Cell. 2021. PMID: 34655525 Free PMC article.
Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease.
Kathiriya IS, Rao KS, Iacono G, Devine WP, Blair AP, Hota SK, Lai MH, Garay BI, Thomas R, Gong HZ, Wasson LK, Goyal P, Sukonnik T, Hu KM, Akgun GA, Bernard LD, Akerberg BN, Gu F, Li K, Speir ML, Haeussler M, Pu WT, Stuart JM, Seidman CE, Seidman JG, Heyn H, Bruneau BG. Kathiriya IS, et al. Among authors: wasson lk. Dev Cell. 2021 Feb 8;56(3):292-309.e9. doi: 10.1016/j.devcel.2020.11.020. Epub 2020 Dec 14. Dev Cell. 2021. PMID: 33321106 Free PMC article.
GATA6 mutations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm.
Sharma A, Wasson LK, Willcox JA, Morton SU, Gorham JM, DeLaughter DM, Neyazi M, Schmid M, Agarwal R, Jang MY, Toepfer CN, Ward T, Kim Y, Pereira AC, DePalma SR, Tai A, Kim S, Conner D, Bernstein D, Gelb BD, Chung WK, Goldmuntz E, Porter G, Tristani-Firouzi M, Srivastava D, Seidman JG, Seidman CE; Pediatric Cardiac Genomics Consortium. Sharma A, et al. Among authors: wasson lk. Elife. 2020 Oct 15;9:e53278. doi: 10.7554/eLife.53278. Elife. 2020. PMID: 33054971 Free PMC article.
Genomic analyses implicate noncoding de novo variants in congenital heart disease.
Richter F, Morton SU, Kim SW, Kitaygorodsky A, Wasson LK, Chen KM, Zhou J, Qi H, Patel N, DePalma SR, Parfenov M, Homsy J, Gorham JM, Manheimer KB, Velinder M, Farrell A, Marth G, Schadt EE, Kaltman JR, Newburger JW, Giardini A, Goldmuntz E, Brueckner M, Kim R, Porter GA Jr, Bernstein D, Chung WK, Srivastava D, Tristani-Firouzi M, Troyanskaya OG, Dickel DE, Shen Y, Seidman JG, Seidman CE, Gelb BD. Richter F, et al. Among authors: wasson lk. Nat Genet. 2020 Aug;52(8):769-777. doi: 10.1038/s41588-020-0652-z. Epub 2020 Jun 29. Nat Genet. 2020. PMID: 32601476 Free PMC article. Clinical Trial.