Dorighi KM - Search Results

1

A versatile, high-efficiency platform for CRISPR-based gene activation.

Heidersbach AJ, Dorighi KM, Gomez JA, Jacobi AM, Haley B. Heidersbach AJ, et al. Among authors: dorighi km. Nat Commun. 2023 Feb 17;14(1):902. doi: 10.1038/s41467-023-36452-w. Nat Commun. 2023. PMID: 36804928 Free PMC article.

2

Potent and selective binders of the E3 ubiquitin ligase ZNRF3 stimulate Wnt signaling and intestinal organoid growth.

Kschonsak YT, Gao X, Miller SE, Hwang S, Marei H, Wu P, Li Y, Ruiz K, Dorighi K, Holokai L, Perampalam P, Tsai WK, Kee YS, Agard NJ, Harris SF, Hannoush RN, de Sousa E Melo F. Kschonsak YT, et al. Cell Chem Biol. 2023 Dec 5:S2451-9456(23)00421-X. doi: 10.1016/j.chembiol.2023.11.006. Online ahead of print. Cell Chem Biol. 2023. PMID: 38056465

3

Accelerated drug-resistant variant discovery with an enhanced, scalable mutagenic base editor platform.

Dorighi KM, Zhu A, Fortin JP, Hung-Hao Lo J, Sudhamsu J, Wendorff TJ, Durinck S, Callow M, Foster SA, Haley B. Dorighi KM, et al. Cell Rep. 2024 Jun 4;43(6):114313. doi: 10.1016/j.celrep.2024.114313. Online ahead of print. Cell Rep. 2024. PMID: 38838224 Free article.

4

Enhancer-associated H3K4 methylation safeguards in vitro germline competence.

Bleckwehl T, Crispatzu G, Schaaf K, Respuela P, Bartusel M, Benson L, Clark SJ, Dorighi KM, Barral A, Laugsch M, van IJcken WFJ, Manzanares M, Wysocka J, Reik W, Rada-Iglesias Á. Bleckwehl T, et al. Among authors: dorighi km. Nat Commun. 2021 Oct 1;12(1):5771. doi: 10.1038/s41467-021-26065-6. Nat Commun. 2021. PMID: 34599190 Free PMC article.

5

Histone H3 lysine 4 monomethylation modulates long-range chromatin interactions at enhancers.

Yan J, Chen SA, Local A, Liu T, Qiu Y, Dorighi KM, Preissl S, Rivera CM, Wang C, Ye Z, Ge K, Hu M, Wysocka J, Ren B. Yan J, et al. Among authors: dorighi km. Cell Res. 2018 Mar;28(3):387. doi: 10.1038/cr.2018.18. Cell Res. 2018. PMID: 29497152 Free PMC article.

6

Histone H3 lysine 4 monomethylation modulates long-range chromatin interactions at enhancers.

Yan J, Chen SA, Local A, Liu T, Qiu Y, Dorighi KM, Preissl S, Rivera CM, Wang C, Ye Z, Ge K, Hu M, Wysocka J, Ren B. Yan J, et al. Among authors: dorighi km. Cell Res. 2018 Feb;28(2):204-220. doi: 10.1038/cr.2018.1. Epub 2018 Jan 9. Cell Res. 2018. PMID: 29313530 Free PMC article.

7

Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation.

Dorighi KM, Swigut T, Henriques T, Bhanu NV, Scruggs BS, Nady N, Still CD 2nd, Garcia BA, Adelman K, Wysocka J. Dorighi KM, et al. Mol Cell. 2017 May 18;66(4):568-576.e4. doi: 10.1016/j.molcel.2017.04.018. Epub 2017 May 5. Mol Cell. 2017. PMID: 28483418 Free PMC article.

8

The trithorax group proteins Kismet and ASH1 promote H3K36 dimethylation to counteract Polycomb group repression in Drosophila.

Dorighi KM, Tamkun JW. Dorighi KM, et al. Development. 2013 Oct;140(20):4182-92. doi: 10.1242/dev.095786. Epub 2013 Sep 4. Development. 2013. PMID: 24004944 Free PMC article.

9

The Drosophila MI-2 chromatin-remodeling factor regulates higher-order chromatin structure and cohesin dynamics in vivo.

Fasulo B, Deuring R, Murawska M, Gause M, Dorighi KM, Schaaf CA, Dorsett D, Brehm A, Tamkun JW. Fasulo B, et al. Among authors: dorighi km. PLoS Genet. 2012;8(8):e1002878. doi: 10.1371/journal.pgen.1002878. Epub 2012 Aug 9. PLoS Genet. 2012. PMID: 22912596 Free PMC article.

10

Integration of a splicing regulatory network within the meiotic gene expression program of Saccharomyces cerevisiae.

Munding EM, Igel AH, Shiue L, Dorighi KM, Treviño LR, Ares M Jr. Munding EM, et al. Among authors: dorighi km. Genes Dev. 2010 Dec 1;24(23):2693-704. doi: 10.1101/gad.1977410. Genes Dev. 2010. PMID: 21123654 Free PMC article.

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