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A noncanonical IRAK4-IRAK1 pathway counters DNA damage-induced apoptosis independently of TLR/IL-1R signaling.
Sci Signal. 2023 Dec 19;16(816):eadh3449. doi: 10.1126/scisignal.adh3449. Epub 2023 Dec 19.
Sci Signal. 2023.
PMID: 38113335
A Non-Canonical IRAK Signaling Pathway Triggered by DNA Damage.
Li Y, Shah RB, Sarti S, Belcher AL, Lee BJ, Gorbatenko A, Nemati F, Yu I, Stanley Z, Shao Z, Silva JM, Zha S, Sidi S.
Li Y, et al. Among authors: belcher al.
bioRxiv [Preprint]. 2023 Feb 8:2023.02.08.527716. doi: 10.1101/2023.02.08.527716.
bioRxiv. 2023.
PMID: 36798275
Free PMC article.
Preprint.
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FANCI functions as a repair/apoptosis switch in response to DNA crosslinks.
Shah RB, Kernan JL, van Hoogstraten A, Ando K, Li Y, Belcher AL, Mininger I, Bussenault AM, Raman R, Ramanagoudr-Bhojappa R, Huang TT, D'Andrea AD, Chandrasekharappa SC, Aggarwal AK, Thompson R, Sidi S.
Shah RB, et al. Among authors: belcher al.
Dev Cell. 2021 Aug 9;56(15):2207-2222.e7. doi: 10.1016/j.devcel.2021.06.010. Epub 2021 Jul 12.
Dev Cell. 2021.
PMID: 34256011
Free PMC article.
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