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Human papillomavirus E6/E7 oncoproteins promote radiotherapy-mediated tumor suppression by globally hijacking host DNA damage repair.
Bruyere D, Roncarati P, Lebeau A, Lerho T, Poulain F, Hendrick E, Pilard C, Reynders C, Ancion M, Luyckx M, Renard M, Jacob Y, Twizere JC, Peiffer R, Peulen O, Delvenne P, Hubert P, McBride A, Gillet N, Masson M, Herfs M. Bruyere D, et al. Among authors: hubert p. Theranostics. 2023 Jan 31;13(3):1130-1149. doi: 10.7150/thno.78091. eCollection 2023. Theranostics. 2023. PMID: 36793865 Free PMC article.
Extracellular HMGB1 blockade inhibits tumor growth through profoundly remodeling immune microenvironment and enhances checkpoint inhibitor-based immunotherapy.
Hubert P, Roncarati P, Demoulin S, Pilard C, Ancion M, Reynders C, Lerho T, Bruyere D, Lebeau A, Radermecker C, Meunier M, Nokin MJ, Hendrick E, Peulen O, Delvenne P, Herfs M. Hubert P, et al. J Immunother Cancer. 2021 Mar;9(3):e001966. doi: 10.1136/jitc-2020-001966. J Immunother Cancer. 2021. PMID: 33712445 Free PMC article.
HPV infection alters vaginal microbiome through down-regulating host mucosal innate peptides used by Lactobacilli as amino acid sources.
Lebeau A, Bruyere D, Roncarati P, Peixoto P, Hervouet E, Cobraiville G, Taminiau B, Masson M, Gallego C, Mazzucchelli G, Smargiasso N, Fleron M, Baiwir D, Hendrick E, Pilard C, Lerho T, Reynders C, Ancion M, Greimers R, Twizere JC, Daube G, Schlecht-Louf G, Bachelerie F, Combes JD, Melin P, Fillet M, Delvenne P, Hubert P, Herfs M. Lebeau A, et al. Among authors: hubert p. Nat Commun. 2022 Feb 28;13(1):1076. doi: 10.1038/s41467-022-28724-8. Nat Commun. 2022. PMID: 35228537 Free PMC article.
ΔNp63 isoform-mediated β-defensin family up-regulation is associated with (lymph)angiogenesis and poor prognosis in patients with squamous cell carcinoma.
Suarez-Carmona M, Hubert P, Gonzalez A, Duray A, Roncarati P, Erpicum C, Boniver J, Castronovo V, Noel A, Saussez S, Peulen O, Delvenne P, Herfs M. Suarez-Carmona M, et al. Among authors: hubert p. Oncotarget. 2014 Apr 15;5(7):1856-68. doi: 10.18632/oncotarget.1819. Oncotarget. 2014. PMID: 24732135 Free PMC article.
Cancer immunotherapy: it's time to better predict patients' response.
Pilard C, Ancion M, Delvenne P, Jerusalem G, Hubert P, Herfs M. Pilard C, et al. Among authors: hubert p. Br J Cancer. 2021 Sep;125(7):927-938. doi: 10.1038/s41416-021-01413-x. Epub 2021 Jun 10. Br J Cancer. 2021. PMID: 34112949 Free PMC article. Review.
Mucosal junctions: open doors to HPV and HIV infections?
Herfs M, Hubert P, Moutschen M, Delvenne P. Herfs M, et al. Among authors: hubert p. Trends Microbiol. 2011 Mar;19(3):114-20. doi: 10.1016/j.tim.2010.12.006. Epub 2011 Jan 7. Trends Microbiol. 2011. PMID: 21216598
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