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Design and Synthesis of Newly Synthesized Acrylamide Derivatives as Potential Chemotherapeutic Agents against MCF-7 Breast Cancer Cell Line Lodged on PEGylated Bilosomal Nano-Vesicles for Improving Cytotoxic Activity.
Zaki I, Abou-Elkhair RAI, Abu Almaaty AH, A Abu Ali O, Fayad E, Ahmed Gaafar AG, Zakaria MY. Zaki I, et al. Pharmaceuticals (Basel). 2021 Oct 4;14(10):1021. doi: 10.3390/ph14101021. Pharmaceuticals (Basel). 2021. PMID: 34681245 Free PMC article.
Novel topoisomerase II/EGFR dual inhibitors: design, synthesis and docking studies of naphtho[2',3':4,5]thiazolo[3,2-a]pyrimidine hybrids as potential anticancer agents with apoptosis inducing activity.
Mourad MAE, Abo Elmaaty A, Zaki I, Mourad AAE, Hofni A, Khodir AE, Aboubakr EM, Elkamhawy A, Roh EJ, Al-Karmalawy AA. Mourad MAE, et al. Among authors: zaki i. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2205043. doi: 10.1080/14756366.2023.2205043. J Enzyme Inhib Med Chem. 2023. PMID: 37165800 Free PMC article.
Design, synthesis, anti-inflammatory evaluation, and molecular modelling of new coumarin-based analogs combined curcumin and other heterocycles as potential TNF-α production inhibitors via upregulating Nrf2/HO-1, downregulating AKT/mTOR signalling pathways and downregulating NF-κB in LPS induced macrophages.
Ghany LMAA, Beshay BY, Youssef Moustafa AM, Maghrabi AHA, Ali EHK, Saleem RM, Zaki I, Ryad N. Ghany LMAA, et al. Among authors: zaki i. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2243551. doi: 10.1080/14756366.2023.2243551. J Enzyme Inhib Med Chem. 2023. PMID: 37558232 Free PMC article.
90 results