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Harnessing transcriptionally driven chromosomal instability adaptation to target therapy-refractory lethal prostate cancer.
Dhital B, Santasusagna S, Kirthika P, Xu M, Li P, Carceles-Cordon M, Soni RK, Li Z, Hendrickson RC, Schiewer MJ, Kelly WK, Sternberg CN, Luo J, Lujambio A, Cordon-Cardo C, Alvarez-Fernandez M, Malumbres M, Huang H, Ertel A, Domingo-Domenech J, Rodriguez-Bravo V. Dhital B, et al. Among authors: malumbres m. Cell Rep Med. 2023 Feb 21;4(2):100937. doi: 10.1016/j.xcrm.2023.100937. Epub 2023 Feb 13. Cell Rep Med. 2023. PMID: 36787737 Free PMC article.
Targeting aneuploidy for cancer therapy.
Manchado E, Malumbres M. Manchado E, et al. Among authors: malumbres m. Cell. 2011 Feb 18;144(4):465-6. doi: 10.1016/j.cell.2011.01.037. Cell. 2011. PMID: 21335229 Free article.
Greatwall is essential to prevent mitotic collapse after nuclear envelope breakdown in mammals.
Álvarez-Fernández M, Sánchez-Martínez R, Sanz-Castillo B, Gan PP, Sanz-Flores M, Trakala M, Ruiz-Torres M, Lorca T, Castro A, Malumbres M. Álvarez-Fernández M, et al. Among authors: malumbres m. Proc Natl Acad Sci U S A. 2013 Oct 22;110(43):17374-9. doi: 10.1073/pnas.1310745110. Epub 2013 Oct 7. Proc Natl Acad Sci U S A. 2013. PMID: 24101512 Free PMC article.
An Atypical Oncogene Within the Atypical E2Fs.
Álvarez-Fernández M, Malumbres M. Álvarez-Fernández M, et al. Among authors: malumbres m. J Natl Cancer Inst. 2015 Jun 18;107(9):djv180. doi: 10.1093/jnci/djv180. Print 2015 Sep. J Natl Cancer Inst. 2015. PMID: 26089542 Free PMC article. No abstract available.
A link between lipid metabolism and epithelial-mesenchymal transition provides a target for colon cancer therapy.
Sánchez-Martínez R, Cruz-Gil S, Gómez de Cedrón M, Álvarez-Fernández M, Vargas T, Molina S, García B, Herranz J, Moreno-Rubio J, Reglero G, Pérez-Moreno M, Feliu J, Malumbres M, Ramírez de Molina A. Sánchez-Martínez R, et al. Among authors: malumbres m. Oncotarget. 2015 Nov 17;6(36):38719-36. doi: 10.18632/oncotarget.5340. Oncotarget. 2015. PMID: 26451612 Free PMC article.
Therapeutic relevance of the PP2A-B55 inhibitory kinase MASTL/Greatwall in breast cancer.
Álvarez-Fernández M, Sanz-Flores M, Sanz-Castillo B, Salazar-Roa M, Partida D, Zapatero-Solana E, Ali HR, Manchado E, Lowe S, VanArsdale T, Shields D, Caldas C, Quintela-Fandino M, Malumbres M. Álvarez-Fernández M, et al. Among authors: malumbres m. Cell Death Differ. 2018 May;25(5):828-840. doi: 10.1038/s41418-017-0024-0. Epub 2017 Dec 11. Cell Death Differ. 2018. PMID: 29229993 Free PMC article.
222 results