Jackson SP - Search Results

1

Revolutionizing DNA repair research and cancer therapy with CRISPR-Cas screens.

Awwad SW, Serrano-Benitez A, Thomas JC, Gupta V, Jackson SP. Awwad SW, et al. Among authors: jackson sp. Nat Rev Mol Cell Biol. 2023 Jul;24(7):477-494. doi: 10.1038/s41580-022-00571-x. Epub 2023 Feb 13. Nat Rev Mol Cell Biol. 2023. PMID: 36781955 Review.

2

The Mre11 complex: at the crossroads of dna repair and checkpoint signalling.

D'Amours D, Jackson SP. D'Amours D, et al. Among authors: jackson sp. Nat Rev Mol Cell Biol. 2002 May;3(5):317-27. doi: 10.1038/nrm805. Nat Rev Mol Cell Biol. 2002. PMID: 11988766 Review.

3

The DNA-damage response in human biology and disease.

Jackson SP, Bartek J. Jackson SP, et al. Nature. 2009 Oct 22;461(7267):1071-8. doi: 10.1038/nature08467. Nature. 2009. PMID: 19847258 Free PMC article. Review.

4

Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair.

Polo SE, Blackford AN, Chapman JR, Baskcomb L, Gravel S, Rusch A, Thomas A, Blundred R, Smith P, Kzhyshkowska J, Dobner T, Taylor AM, Turnell AS, Stewart GS, Grand RJ, Jackson SP. Polo SE, et al. Among authors: jackson sp. Mol Cell. 2012 Feb 24;45(4):505-16. doi: 10.1016/j.molcel.2011.12.035. Mol Cell. 2012. PMID: 22365830 Free PMC article.

5

Regulation of DNA damage responses by ubiquitin and SUMO.

Jackson SP, Durocher D. Jackson SP, et al. Mol Cell. 2013 Mar 7;49(5):795-807. doi: 10.1016/j.molcel.2013.01.017. Epub 2013 Feb 14. Mol Cell. 2013. PMID: 23416108 Free article. Review.

6

Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity.

Nishi R, Wijnhoven P, le Sage C, Tjeertes J, Galanty Y, Forment JV, Clague MJ, Urbé S, Jackson SP. Nishi R, et al. Among authors: jackson sp. Nat Cell Biol. 2014 Oct;16(10):1016-26, 1-8. doi: 10.1038/ncb3028. Epub 2014 Sep 7. Nat Cell Biol. 2014. PMID: 25194926 Free PMC article.

7

CtIP tetramer assembly is required for DNA-end resection and repair.

Davies OR, Forment JV, Sun M, Belotserkovskaya R, Coates J, Galanty Y, Demir M, Morton CR, Rzechorzek NJ, Jackson SP, Pellegrini L. Davies OR, et al. Among authors: jackson sp. Nat Struct Mol Biol. 2015 Feb;22(2):150-157. doi: 10.1038/nsmb.2937. Epub 2015 Jan 5. Nat Struct Mol Biol. 2015. PMID: 25558984 Free PMC article.

8

Systematic E2 screening reveals a UBE2D-RNF138-CtIP axis promoting DNA repair.

Schmidt CK, Galanty Y, Sczaniecka-Clift M, Coates J, Jhujh S, Demir M, Cornwell M, Beli P, Jackson SP. Schmidt CK, et al. Among authors: jackson sp. Nat Cell Biol. 2015 Nov;17(11):1458-1470. doi: 10.1038/ncb3260. Epub 2015 Oct 26. Nat Cell Biol. 2015. PMID: 26502057 Free PMC article.

9

ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response.

Blackford AN, Jackson SP. Blackford AN, et al. Among authors: jackson sp. Mol Cell. 2017 Jun 15;66(6):801-817. doi: 10.1016/j.molcel.2017.05.015. Mol Cell. 2017. PMID: 28622525 Free article. Review.

10

Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells.

Dev H, Chiang TW, Lescale C, de Krijger I, Martin AG, Pilger D, Coates J, Sczaniecka-Clift M, Wei W, Ostermaier M, Herzog M, Lam J, Shea A, Demir M, Wu Q, Yang F, Fu B, Lai Z, Balmus G, Belotserkovskaya R, Serra V, O'Connor MJ, Bruna A, Beli P, Pellegrini L, Caldas C, Deriano L, Jacobs JJL, Galanty Y, Jackson SP. Dev H, et al. Among authors: jackson sp. Nat Cell Biol. 2018 Aug;20(8):954-965. doi: 10.1038/s41556-018-0140-1. Epub 2018 Jul 18. Nat Cell Biol. 2018. PMID: 30022119 Free PMC article.

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