Li C - Search Results

1

Concentration QTc analysis of giredestrant: Overcoming QT/heart rate confounding in the presence of drug-induced heart rate changes.

Brooks L, Dolton M, Langenhorst J, Yoshida K, Lien YTK, Malhi V, Li C, Perez-Moreno P, Bond J, Chen YC, Yu J. Brooks L, et al. Among authors: li c. Clin Transl Sci. 2023 May;16(5):823-834. doi: 10.1111/cts.13491. Epub 2023 Feb 22. Clin Transl Sci. 2023. PMID: 36772881 Free PMC article.

2

Prediction of Human Pharmacokinetics of Antibody-Drug Conjugates From Nonclinical Data.

Li C, Zhang C, Deng R, Leipold D, Li D, Latifi B, Gao Y, Zhang C, Li Z, Miles D, Chen SC, Samineni D, Wang B, Agarwal P, Lu D, Prabhu S, Girish S, Kamath AV. Li C, et al. Among authors: li d, li z. Clin Transl Sci. 2019 Sep;12(5):534-544. doi: 10.1111/cts.12649. Epub 2019 Jun 11. Clin Transl Sci. 2019. PMID: 31115997 Free PMC article.

3

Tumor Dynamic Model-Based Decision Support for Phase Ib/II Combination Studies: A Retrospective Assessment Based on Resampling of the Phase III Study IMpower150.

Bruno R, Marchand M, Yoshida K, Chan P, Li H, Zou W, Mercier F, Chanu P, Wu B, Lee A, Li C, Jin JY, Maitland ML, Reck M, Socinski MA. Bruno R, et al. Among authors: li c, li h. Clin Cancer Res. 2023 Mar 14;29(6):1047-1055. doi: 10.1158/1078-0432.CCR-22-2323. Clin Cancer Res. 2023. PMID: 36595566 Free PMC article. Clinical Trial.

4

Pharmacokinetics of biologics in gastric cancer.

Li J, Turner DC, Li F, Chen X, Liao MZ, Li C. Li J, et al. Among authors: li f, li c. Clin Transl Sci. 2023 Apr;16(4):564-574. doi: 10.1111/cts.13474. Epub 2023 Jan 18. Clin Transl Sci. 2023. PMID: 36631818 Free PMC article. Review.

5

Support to early clinical decisions in drug development and personalised medicine with checkpoint inhibitors using dynamic biomarker-overall survival models.

Bruno R, Chanu P, Kågedal M, Mercier F, Yoshida K, Guedj J, Li C, Beyer U, Jin JY. Bruno R, et al. Among authors: li c. Br J Cancer. 2023 Oct;129(9):1383-1388. doi: 10.1038/s41416-023-02190-5. Epub 2023 Feb 10. Br J Cancer. 2023. PMID: 36765177 Free PMC article. Review.

6

Ethnic sensitivity assessment: Polatuzumab vedotin pharmacokinetics in Asian and non-Asian patients with previously untreated diffuse large B-cell lymphoma in POLARIX.

Liao MZ, Deng R, Gibiansky L, Lu T, Agarwal P, Dere R, Lee C, Hirata J, Herbaux C, Salles G, Li C, Miles D. Liao MZ, et al. Among authors: li c. Clin Transl Sci. 2023 Dec;16(12):2744-2755. doi: 10.1111/cts.13669. Epub 2023 Oct 31. Clin Transl Sci. 2023. PMID: 37864313 Free PMC article.

7

Confounding factors in exposure-response analyses and mitigation strategies for monoclonal antibodies in oncology.

Kawakatsu S, Bruno R, Kågedal M, Li C, Girish S, Joshi A, Wu B. Kawakatsu S, et al. Among authors: li c. Br J Clin Pharmacol. 2021 Jun;87(6):2493-2501. doi: 10.1111/bcp.14662. Epub 2020 Dec 7. Br J Clin Pharmacol. 2021. PMID: 33217012 Free article. Review.

8

Impact of Dose Delays and Alternative Dosing Regimens on Pertuzumab Pharmacokinetics.

Liu SN, Lu T, Jin JY, Li C, Girish S, Melnikov F, Badovinac Crnjevic T, Machackova Z, Restuccia E, Kirschbrown WP. Liu SN, et al. Among authors: li c. J Clin Pharmacol. 2021 Aug;61(8):1096-1105. doi: 10.1002/jcph.1855. Epub 2021 Jul 7. J Clin Pharmacol. 2021. PMID: 33719071 Free PMC article.

9

Patient, industry, and regulatory perspective on antibody-drug conjugates dose optimization.

Hamed S, Li C, Liao MZ, Warwick L, Zhou Z. Hamed S, et al. Among authors: li c. Clin Transl Sci. 2024 Mar;17(3):e13759. doi: 10.1111/cts.13759. Clin Transl Sci. 2024. PMID: 38501292 Free PMC article. No abstract available.

10

Time-to-Event Modeling of Peripheral Neuropathy: Platform Analysis of Eight Valine-Citrulline-Monomethylauristatin E Antibody-Drug Conjugates.

Kågedal M, Samineni D, Gillespie WR, Lu D, Fine BM, Girish S, Li C, Jin JY. Kågedal M, et al. Among authors: li c. CPT Pharmacometrics Syst Pharmacol. 2019 Aug;8(8):606-615. doi: 10.1002/psp4.12442. Epub 2019 Jul 10. CPT Pharmacometrics Syst Pharmacol. 2019. PMID: 31207190 Free PMC article.

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