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Genome-wide epigenetic and mRNA-expression profiling followed by CRISPR/Cas9-mediated gene-disruptions corroborate the MIR141/MIR200C-ZEB1/ZEB2-FGFR1 axis in acquired EMT-associated EGFR TKI-resistance in NSCLC cells.
Vad-Nielsen J, Staunstrup NH, Kjeldsen ML, Dybdal N, Flandin G, De Stradis C, Daugaard TF, Vilsbøll-Larsen T, Maansson CT, Doktor TK, Sorensen BS, Nielsen AL. Vad-Nielsen J, et al. Among authors: nielsen al. Transl Lung Cancer Res. 2023 Jan 31;12(1):42-65. doi: 10.21037/tlcr-22-507. Epub 2023 Jan 13. Transl Lung Cancer Res. 2023. PMID: 36762066 Free PMC article.
Regulatory dissection of the CBX5 and hnRNPA1 bi-directional promoter in human breast cancer cells reveals novel transcript variants differentially associated with HP1α down-regulation in metastatic cells.
Vad-Nielsen J, Jakobsen KR, Daugaard TF, Thomsen R, Brügmann A, Sørensen BS, Nielsen AL. Vad-Nielsen J, et al. Among authors: nielsen al. BMC Cancer. 2016 Jan 20;16:32. doi: 10.1186/s12885-016-2059-x. BMC Cancer. 2016. PMID: 26791953 Free PMC article.
Hypomethylation of FAM63B in bipolar disorder patients.
Starnawska A, Demontis D, McQuillin A, O'Brien NL, Staunstrup NH, Mors O, Nielsen AL, Børglum AD, Nyegaard M. Starnawska A, et al. Among authors: nielsen al. Clin Epigenetics. 2016 May 11;8:52. doi: 10.1186/s13148-016-0221-6. eCollection 2016. Clin Epigenetics. 2016. PMID: 27175219 Free PMC article.
CACNA1C hypermethylation is associated with bipolar disorder.
Starnawska A, Demontis D, Pen A, Hedemand A, Nielsen AL, Staunstrup NH, Grove J, Als TD, Jarram A, O'Brien NL, Mors O, McQuillin A, Børglum AD, Nyegaard M. Starnawska A, et al. Among authors: nielsen al. Transl Psychiatry. 2016 Jun 7;6(6):e831. doi: 10.1038/tp.2016.99. Transl Psychiatry. 2016. PMID: 27271857 Free PMC article.
336 results