Maier MA - Search Results

1

Metabolically Stable Anomeric Linkages Containing GalNAc-siRNA Conjugates: An Interplay among ASGPR, Glycosidase, and RISC Pathways.

Kandasamy P, Mori S, Matsuda S, Erande N, Datta D, Willoughby JLS, Taneja N, O'Shea J, Bisbe A, Manoharan RM, Yucius K, Nguyen T, Indrakanti R, Gupta S, Gilbert JA, Racie T, Chan A, Liu J, Hutabarat R, Nair JK, Charisse K, Maier MA, Rajeev KG, Egli M, Manoharan M. Kandasamy P, et al. Among authors: maier ma. J Med Chem. 2023 Feb 23;66(4):2506-2523. doi: 10.1021/acs.jmedchem.2c01337. Epub 2023 Feb 9. J Med Chem. 2023. PMID: 36757090

2

Synthesis of chimeric oligonucleotides containing phosphodiester, phosphorothioate, and phosphoramidate linkages.

Maier MA, Guzaev AP, Manoharan M. Maier MA, et al. Org Lett. 2000 Jun 29;2(13):1819-22. doi: 10.1021/ol005842h. Org Lett. 2000. PMID: 10891166

3

Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experiments.

Tereshko V, Wilds CJ, Minasov G, Prakash TP, Maier MA, Howard A, Wawrzak Z, Manoharan M, Egli M. Tereshko V, et al. Among authors: maier ma. Nucleic Acids Res. 2001 Mar 1;29(5):1208-15. doi: 10.1093/nar/29.5.1208. Nucleic Acids Res. 2001. PMID: 11222771 Free PMC article.

4

Synthesis of novel 3'-C-methylene thymidine and 5-methyluridine/cytidine H-phosphonates and phosphonamidites for new backbone modification of oligonucleotides.

An H, Wang T, Maier MA, Manoharan M, Ross BS, Cook PD. An H, et al. Among authors: maier ma. J Org Chem. 2001 Apr 20;66(8):2789-801. doi: 10.1021/jo001699u. J Org Chem. 2001. PMID: 11304203

5

High-affinity peptide nucleic acid oligomers containing tricyclic cytosine analogues.

Rajeev KG, Maier MA, Lesnik EA, Manoharan M. Rajeev KG, et al. Among authors: maier ma. Org Lett. 2002 Dec 12;4(25):4395-8. doi: 10.1021/ol027026a. Org Lett. 2002. PMID: 12465896

6

Direct observation of a cytosine analogue that forms five hydrogen bonds to guanosine: guanidino G-clamp.

Wilds CJ, Maier MA, Tereshko V, Manoharan M, Egli M. Wilds CJ, et al. Among authors: maier ma. Angew Chem Int Ed Engl. 2002 Jan 4;41(1):115-7. doi: 10.1002/1521-3773(20020104)41:1<115::aid-anie115>3.0.co;2-r. Angew Chem Int Ed Engl. 2002. PMID: 12491456 No abstract available.

7

Synthesis of antisense oligonucleotides conjugated to a multivalent carbohydrate cluster for cellular targeting.

Maier MA, Yannopoulos CG, Mohamed N, Roland A, Fritz H, Mohan V, Just G, Manoharan M. Maier MA, et al. Bioconjug Chem. 2003 Jan-Feb;14(1):18-29. doi: 10.1021/bc020028v. Bioconjug Chem. 2003. PMID: 12526688

8

Structure-activity relationship study on a simple cationic peptide motif for cellular delivery of antisense peptide nucleic acid.

Albertshofer K, Siwkowski AM, Wancewicz EV, Esau CC, Watanabe T, Nishihara KC, Kinberger GA, Malik L, Eldrup AB, Manoharan M, Geary RS, Monia BP, Swayze EE, Griffey RH, Bennett CF, Maier MA. Albertshofer K, et al. Among authors: maier ma. J Med Chem. 2005 Oct 20;48(21):6741-9. doi: 10.1021/jm050490b. J Med Chem. 2005. PMID: 16220989

9

Evaluation of basic amphipathic peptides for cellular delivery of antisense peptide nucleic acids.

Maier MA, Esau CC, Siwkowski AM, Wancewicz EV, Albertshofer K, Kinberger GA, Kadaba NS, Watanabe T, Manoharan M, Bennett CF, Griffey RH, Swayze EE. Maier MA, et al. J Med Chem. 2006 Apr 20;49(8):2534-42. doi: 10.1021/jm051275y. J Med Chem. 2006. PMID: 16610796

10

Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme.

Li F, Pallan PS, Maier MA, Rajeev KG, Mathieu SL, Kreutz C, Fan Y, Sanghvi J, Micura R, Rozners E, Manoharan M, Egli M. Li F, et al. Among authors: maier ma. Nucleic Acids Res. 2007;35(19):6424-38. doi: 10.1093/nar/gkm664. Epub 2007 Sep 18. Nucleic Acids Res. 2007. PMID: 17881374 Free PMC article.

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