Marrazzo A - Search Results

1

Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5-Fluorouracil and Imidazole-Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells.

Salerno L, Sorrenti V, Pittalà V, Consoli V, Modica MN, Romeo G, Marrazzo A, Giuliano M, Zajdel P, Vanella L, Intagliata S. Salerno L, et al. Among authors: marrazzo a. ChemMedChem. 2023 Apr 17;18(8):e202300047. doi: 10.1002/cmdc.202300047. Epub 2023 Feb 24. ChemMedChem. 2023. PMID: 36756924

2

(+)-cis-N-ethyleneamino-N-normetazocine derivatives. Novel and selective sigma ligands with antagonist properties.

Ronsisvalle G, Marrazzo A, Prezzavento O, Pasquinucci L, Vittorio F, Pittalà V, Pappalardo MS, Cacciaguerra S, Spampinato S. Ronsisvalle G, et al. Among authors: marrazzo a. J Med Chem. 1998 May 7;41(10):1574-80. doi: 10.1021/jm970333f. J Med Chem. 1998. PMID: 9572883

3

Nonpeptide analogues of dynorphin A(1-8): design, synthesis, and pharmacological evaluation of kappa-selective agonists.

Ronsisvalle G, Pasquinucci L, Pittalà V, Marrazzo A, Prezzavento O, Di Toro R, Falcucci B, Spampinato S. Ronsisvalle G, et al. Among authors: marrazzo a. J Med Chem. 2000 Aug 10;43(16):2992-3004. doi: 10.1021/jm990356p. J Med Chem. 2000. PMID: 10956208

4

Novel sigma receptor ligands: synthesis and biological profile.

Prezzavento O, Campisi A, Ronsisvalle S, Li Volti G, Marrazzo A, Bramanti V, Cannavò G, Vanella L, Cagnotto A, Mennini T, Ientile R, Ronsisvalle G. Prezzavento O, et al. Among authors: marrazzo a. J Med Chem. 2007 Mar 8;50(5):951-61. doi: 10.1021/jm0611197. Epub 2007 Feb 13. J Med Chem. 2007. PMID: 17328523

5

Novel imidazole derivatives as heme oxygenase-1 (HO-1) and heme oxygenase-2 (HO-2) inhibitors and their cytotoxic activity in human-derived cancer cell lines.

Salerno L, Pittalà V, Romeo G, Modica MN, Marrazzo A, Siracusa MA, Sorrenti V, Di Giacomo C, Vanella L, Parayath NN, Greish K. Salerno L, et al. Among authors: marrazzo a. Eur J Med Chem. 2015;96:162-72. doi: 10.1016/j.ejmech.2015.04.003. Epub 2015 Apr 7. Eur J Med Chem. 2015. PMID: 25874340

6

(+)-Pentazocine reduces oxidative stress and apoptosis in microglia following hypoxia/reoxygenation injury.

Heiss K, Vanella L, Murabito P, Prezzavento O, Marrazzo A, Castruccio Castracani C, Barbagallo I, Zappalà A, Arena E, Astuto M, Giarratano A, Li Volti G. Heiss K, et al. Among authors: marrazzo a. Neurosci Lett. 2016 Jul 28;626:142-8. doi: 10.1016/j.neulet.2016.05.025. Epub 2016 May 18. Neurosci Lett. 2016. PMID: 27208832

7

New bifunctional antioxidant/σ1 agonist ligands: Preliminary chemico-physical and biological evaluation.

Arena E, Cacciatore I, Cerasa LS, Turkez H, Pittalà V, Pasquinucci L, Marrazzo A, Parenti C, Di Stefano A, Prezzavento O. Arena E, et al. Among authors: marrazzo a. Bioorg Med Chem. 2016 Jul 15;24(14):3149-56. doi: 10.1016/j.bmc.2016.05.045. Epub 2016 May 21. Bioorg Med Chem. 2016. PMID: 27262426

8

Antiangiogenic Effect of (±)-Haloperidol Metabolite II Valproate Ester [(±)-MRJF22] in Human Microvascular Retinal Endothelial Cells.

Olivieri M, Amata E, Vinciguerra S, Fiorito J, Giurdanella G, Drago F, Caporarello N, Prezzavento O, Arena E, Salerno L, Rescifina A, Lupo G, Anfuso CD, Marrazzo A. Olivieri M, et al. Among authors: marrazzo a. J Med Chem. 2016 Nov 10;59(21):9960-9966. doi: 10.1021/acs.jmedchem.6b01039. Epub 2016 Oct 25. J Med Chem. 2016. PMID: 27739690

9

S2RSLDB: a comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands.

Nastasi G, Miceli C, Pittalà V, Modica MN, Prezzavento O, Romeo G, Rescifina A, Marrazzo A, Amata E. Nastasi G, et al. Among authors: marrazzo a. J Cheminform. 2017 Jan 21;9:3. doi: 10.1186/s13321-017-0191-5. eCollection 2017. J Cheminform. 2017. PMID: 28123452 Free PMC article.

10

(+)-Pentazocine attenuates SH-SY5Y cell death, oxidative stress and microglial migration induced by conditioned medium from activated microglia.

Heiss K, Raffaele M, Vanella L, Murabito P, Prezzavento O, Marrazzo A, Aricò G, Castracani CC, Barbagallo I, Zappalà A, Avola R, Li Volti G. Heiss K, et al. Among authors: marrazzo a. Neurosci Lett. 2017 Mar 6;642:86-90. doi: 10.1016/j.neulet.2017.02.005. Epub 2017 Feb 3. Neurosci Lett. 2017. PMID: 28163081

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