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SARS-CoV-2 spike HexaPro formulated in aluminium hydroxide and administered in an accelerated vaccination schedule partially protects Syrian Hamsters against viral challenge despite low neutralizing antibody responses.
Christensen D, Polacek C, Sheward DJ, Hanke L, McInerney G, Murrell B, Hartmann KT, Jensen HE, Zimmermann J, Jungersen G, Illigen KE, Isling LK, Fernandez-Antunez C, Ramirez S, Bukh J, Pedersen GK. Christensen D, et al. Among authors: murrell b. Front Immunol. 2023 Jan 23;14:941281. doi: 10.3389/fimmu.2023.941281. eCollection 2023. Front Immunol. 2023. PMID: 36756130 Free PMC article.
Longitudinal single-cell analysis of SARS-CoV-2-reactive B cells uncovers persistence of early-formed, antigen-specific clones.
Scharf L, Axelsson H, Emmanouilidi A, Mathew NR, Sheward DJ, Leach S, Isakson P, Smirnov IV, Marklund E, Miron N, Andersson LM, Gisslén M, Murrell B, Lundgren A, Bemark M, Angeletti D. Scharf L, et al. Among authors: murrell b. JCI Insight. 2023 Jan 10;8(1):e165299. doi: 10.1172/jci.insight.165299. JCI Insight. 2023. PMID: 36445762 Free PMC article.
Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies.
Pushparaj P, Nicoletto A, Sheward DJ, Das H, Castro Dopico X, Perez Vidakovics L, Hanke L, Chernyshev M, Narang S, Kim S, Fischbach J, Ekström S, McInerney G, Hällberg BM, Murrell B, Corcoran M, Karlsson Hedestam GB. Pushparaj P, et al. Among authors: murrell b. Immunity. 2023 Jan 10;56(1):193-206.e7. doi: 10.1016/j.immuni.2022.12.005. Epub 2022 Dec 12. Immunity. 2023. PMID: 36574772 Free PMC article.
A Multiparametric and High-Throughput Platform for Host-Virus Binding Screens.
Schlegel J, Porebski B, Andronico L, Hanke L, Edwards S, Brismar H, Murrell B, McInerney GM, Fernandez-Capetillo O, Sezgin E. Schlegel J, et al. Among authors: murrell b. Nano Lett. 2023 May 10;23(9):3701-3707. doi: 10.1021/acs.nanolett.2c04884. Epub 2023 Mar 9. Nano Lett. 2023. PMID: 36892970 Free PMC article.
Frequent use of IGHV3-30-3 in SARS-CoV-2 neutralizing antibody responses.
Pushparaj P, Nicoletto A, Dopico XC, Sheward DJ, Kim S, Ekström S, Murrell B, Corcoran M, Karlsson Hedestam GB. Pushparaj P, et al. Among authors: murrell b. Front Virol. 2023 Mar 1;3:1128253. doi: 10.3389/fviro.2023.1128253. Front Virol. 2023. PMID: 37041983 Free PMC article.
Vaccine-induced correlate of protection against fatal COVID-19 in older and frail adults during waves of neutralization-resistant variants of concern: an observational study.
Vikström L, Fjällström P, Gwon YD, Sheward DJ, Wigren-Byström J, Evander M, Bladh O, Widerström M, Molnar C, Rasmussen G, Bennet L, Åberg M, Björk J, Tevell S, Thålin C, Blom K, Klingström J, Murrell B, Ahlm C, Normark J, Johansson AF, Forsell MNE. Vikström L, et al. Among authors: murrell b. Lancet Reg Health Eur. 2023 May 6;30:100646. doi: 10.1016/j.lanepe.2023.100646. Online ahead of print. Lancet Reg Health Eur. 2023. PMID: 37363799 Free PMC article.
Antigen receptor stimulation induces purifying selection against pathogenic mitochondrial tRNA mutations.
Zhang J, Koolmeister C, Han J, Filograna R, Hanke L, Àdori M, Sheward DJ, Teifel S, Gopalakrishna S, Shao Q, Liu Y, Zhu K, Harris RA, McInerney G, Murrell B, Aoun M, Bäckdahl L, Holmdahl R, Pekalski M, Wedell A, Engvall M, Wredenberg A, Karlsson Hedestam GB, Castro Dopico X, Rorbach J. Zhang J, et al. Among authors: murrell b. JCI Insight. 2023 Sep 8;8(17):e167656. doi: 10.1172/jci.insight.167656. JCI Insight. 2023. PMID: 37681412 Free PMC article.
Structural basis of broad SARS-CoV-2 cross-neutralization by affinity-matured public antibodies.
Sheward DJ, Pushparaj P, Das H, Greaney AJ, Kim C, Kim S, Hanke L, Hyllner E, Dyrdak R, Lee J, Dopico XC, Dosenovic P, Peacock TP, McInerney GM, Albert J, Corcoran M, Bloom JD, Murrell B, Karlsson Hedestam GB, Hällberg BM. Sheward DJ, et al. Among authors: murrell b. Cell Rep Med. 2024 May 15:101577. doi: 10.1016/j.xcrm.2024.101577. Online ahead of print. Cell Rep Med. 2024. PMID: 38761799 Free article.
118 results