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Arrest of mouse preterm labor until term delivery by combination therapy with atosiban and mundulone, a natural product with tocolytic efficacy.
Siricilla S, Hansen CJ, Rogers JH, De D, Simpson CL, Waterson AG, Sulikowski GA, Crockett SL, Boatwright N, Reese J, Paria BC, Newton J, Herington JL. Siricilla S, et al. Among authors: waterson ag. Pharmacol Res. 2023 Sep;195:106876. doi: 10.1016/j.phrs.2023.106876. Epub 2023 Aug 1. Pharmacol Res. 2023. PMID: 37536638 Free PMC article.
Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages.
Zarrow JE, Alli-Oluwafuyi AM, Youwakim CM, Kim K, Jenkins AN, Suero IC, Jones MR, Mashhadi Z, Mackie K, Waterson AG, Doran AC, Sulikowski GA, Davies SS. Zarrow JE, et al. Among authors: waterson ag. ACS Chem Biol. 2023 Aug 18;18(8):1891-1904. doi: 10.1021/acschembio.3c00401. Epub 2023 Aug 2. ACS Chem Biol. 2023. PMID: 37531659 Free article.
Arrest of mouse preterm labor until term delivery by combination therapy with atosiban and mundulone, a natural product with tocolytic efficacy.
Siricilla S, Hansen CJ, Rogers JH, De D, Simpson CL, Waterson AG, Sulikowski GA, Crockett SL, Boatwright N, Reese J, Paria BC, Newton J, Herington JL. Siricilla S, et al. Among authors: waterson ag. bioRxiv [Preprint]. 2023 Jun 8:2023.06.06.543921. doi: 10.1101/2023.06.06.543921. bioRxiv. 2023. PMID: 37333338 Free PMC article. Updated. Preprint.
Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages.
Zarrow JE, Alli-Oluwafuyi AM, Youwakim CM, Kim K, Jenkins AN, Suero IC, Jones MR, Mashhadi Z, Mackie KP, Waterson AG, Doran AC, Sulikowski GA, Davies SS. Zarrow JE, et al. Among authors: waterson ag. bioRxiv [Preprint]. 2023 Feb 28:2023.01.25.525554. doi: 10.1101/2023.01.25.525554. bioRxiv. 2023. PMID: 36747693 Free PMC article. Updated. Preprint.
Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRASG12C Inhibitor.
Bröker J, Waterson AG, Smethurst C, Kessler D, Böttcher J, Mayer M, Gmaschitz G, Phan J, Little A, Abbott JR, Sun Q, Gmachl M, Rudolph D, Arnhof H, Rumpel K, Savarese F, Gerstberger T, Mischerikow N, Treu M, Herdeis L, Wunberg T, Gollner A, Weinstabl H, Mantoulidis A, Krämer O, McConnell DB, W Fesik S. Bröker J, et al. Among authors: waterson ag. J Med Chem. 2022 Nov 10;65(21):14614-14629. doi: 10.1021/acs.jmedchem.2c01120. Epub 2022 Oct 27. J Med Chem. 2022. PMID: 36300829 Free PMC article.
High-Content Imaging Platform to Discover Chemical Modulators of Plasma Membrane Rafts.
Fricke N, Raghunathan K, Tiwari A, Stefanski KM, Balakrishnan M, Waterson AG, Capone R, Huang H, Sanders CR, Bauer JA, Kenworthy AK. Fricke N, et al. Among authors: waterson ag. ACS Cent Sci. 2022 Mar 23;8(3):370-378. doi: 10.1021/acscentsci.1c01058. Epub 2022 Feb 21. ACS Cent Sci. 2022. PMID: 35355811 Free PMC article.
Simultaneous Exposure to Intracellular and Extracellular Photosensitizers for the Treatment of Staphylococcus aureus Infections.
Drury SL, Miller AR, Laut CL, Walter AB, Bennett MR, Su M, Bai M, Jing B, Joseph SB, Metzger EJ, Bane CE, Black CC, Macdonald MT, Dutter BF, Romaine IM, Waterson AG, Sulikowski GA, Jansen ED, Crowe JE Jr, Sciotti RJ, Skaar EP. Drury SL, et al. Among authors: waterson ag. Antimicrob Agents Chemother. 2021 Nov 17;65(12):e0091921. doi: 10.1128/AAC.00919-21. Epub 2021 Sep 13. Antimicrob Agents Chemother. 2021. PMID: 34516248 Free PMC article.
Optimization of ether and aniline based inhibitors of lactate dehydrogenase.
Christov PP, Kim K, Jana S, Romaine IM, Rai G, Mott BT, Allweil AA, Lamers A, Brimacombe KR, Urban DJ, Lee TD, Hu X, Lukacs CM, Davies DR, Jadhav A, Hall MD, Green N, Moore WJ, Stott GM, Flint AJ, Maloney DJ, Sulikowski GA, Waterson AG. Christov PP, et al. Among authors: waterson ag. Bioorg Med Chem Lett. 2021 Jun 1;41:127974. doi: 10.1016/j.bmcl.2021.127974. Epub 2021 Mar 24. Bioorg Med Chem Lett. 2021. PMID: 33771585 Free PMC article.
55 results