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Expression of an active Gαs mutant in skeletal stem cells is sufficient and necessary for fibrous dysplasia initiation and maintenance.
Zhao X, Deng P, Iglesias-Bartolome R, Amornphimoltham P, Steffen DJ, Jin Y, Molinolo AA, de Castro LF, Ovejero D, Yuan Q, Chen Q, Han X, Bai D, Taylor SS, Yang Y, Collins MT, Gutkind JS. Zhao X, et al. Among authors: de castro lf. Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E428-E437. doi: 10.1073/pnas.1713710115. Epub 2017 Dec 27. Proc Natl Acad Sci U S A. 2018. PMID: 29282319 Free PMC article.
Skeletal Consequences of Nephropathic Cystinosis.
Florenzano P, Ferreira C, Nesterova G, Roberts MS, Tella SH, de Castro LF, Brown SM, Whitaker A, Pereira RC, Bulas D, Gafni RI, Salusky IB, Gahl WA, Collins MT. Florenzano P, et al. Among authors: de castro lf. J Bone Miner Res. 2018 Oct;33(10):1870-1880. doi: 10.1002/jbmr.3522. Epub 2018 Jul 20. J Bone Miner Res. 2018. PMID: 29905968 Free article.
Denosumab for Fibrous Dysplasia: Promising, but Questions Remain.
Collins MT, de Castro LF, Boyce AM. Collins MT, et al. Among authors: de castro lf. J Clin Endocrinol Metab. 2020 Nov 1;105(11):e4179-80. doi: 10.1210/clinem/dgaa091. J Clin Endocrinol Metab. 2020. PMID: 32478399 Free PMC article. No abstract available.
Novel Majeed Syndrome-Causing LPIN2 Mutations Link Bone Inflammation to Inflammatory M2 Macrophages and Accelerated Osteoclastogenesis.
Bhuyan F, de Jesus AA, Mitchell J, Leikina E, VanTries R, Herzog R, Onel KB, Oler A, Montealegre Sanchez GA, Johnson KA, Bichell L, Marrero B, De Castro LF, Huang Y, Calvo KR, Collins MT, Ganesan S, Chernomordik LV, Ferguson PJ, Goldbach-Mansky R. Bhuyan F, et al. Among authors: de castro lf, de jesus aa. Arthritis Rheumatol. 2021 Jun;73(6):1021-1032. doi: 10.1002/art.41624. Epub 2021 May 9. Arthritis Rheumatol. 2021. PMID: 33314777 Free PMC article.
Fibrous dysplasia animal models: A systematic review.
Hopkins C, de Castro LF, Corsi A, Boyce A, Collins MT, Riminucci M, Heegaard AM. Hopkins C, et al. Among authors: de castro lf. Bone. 2022 Feb;155:116270. doi: 10.1016/j.bone.2021.116270. Epub 2021 Dec 4. Bone. 2022. PMID: 34875396 Free article.
57 results