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Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis.
Fratta P, Sivakumar P, Humphrey J, Lo K, Ricketts T, Oliveira H, Brito-Armas JM, Kalmar B, Ule A, Yu Y, Birsa N, Bodo C, Collins T, Conicella AE, Mejia Maza A, Marrero-Gagliardi A, Stewart M, Mianne J, Corrochano S, Emmett W, Codner G, Groves M, Fukumura R, Gondo Y, Lythgoe M, Pauws E, Peskett E, Stanier P, Teboul L, Hallegger M, Calvo A, Chiò A, Isaacs AM, Fawzi NL, Wang E, Housman DE, Baralle F, Greensmith L, Buratti E, Plagnol V, Fisher EM, Acevedo-Arozena A. Fratta P, et al. EMBO J. 2018 Jun 1;37(11):e98684. doi: 10.15252/embj.201798684. Epub 2018 May 15. EMBO J. 2018. PMID: 29764981 Free PMC article.
Reduced expression of ribosomal proteins relieves microRNA-mediated repression.
Janas MM, Wang E, Love T, Harris AS, Stevenson K, Semmelmann K, Shaffer JM, Chen PH, Doench JG, Yerramilli SV, Neuberg DS, Iliopoulos D, Housman DE, Burge CB, Novina CD. Janas MM, et al. Mol Cell. 2012 Apr 27;46(2):171-86. doi: 10.1016/j.molcel.2012.04.008. Mol Cell. 2012. PMID: 22541556 Free article.
Characterization of FUS mutations in amyotrophic lateral sclerosis using RNA-Seq.
van Blitterswijk M, Wang ET, Friedman BA, Keagle PJ, Lowe P, Leclerc AL, van den Berg LH, Housman DE, Veldink JH, Landers JE. van Blitterswijk M, et al. Among authors: wang et. PLoS One. 2013;8(4):e60788. doi: 10.1371/journal.pone.0060788. Epub 2013 Apr 8. PLoS One. 2013. PMID: 23577159 Free PMC article.
Myospreader improves gene editing in skeletal muscle by myonuclear propagation.
Poukalov KK, Valero MC, Muscato DR, Adams LM, Chun H, Lee YI, Andrade NS, Zeier Z, Sweeney HL, Wang ET. Poukalov KK, et al. Among authors: wang et. Proc Natl Acad Sci U S A. 2024 May 7;121(19):e2321438121. doi: 10.1073/pnas.2321438121. Epub 2024 Apr 30. Proc Natl Acad Sci U S A. 2024. PMID: 38687782
High-throughput mRNA sequencing of human placenta shows sex differences across gestation.
Flowers AE, Gonzalez TL, Wang Y, Santiskulvong C, Clark EL, Novoa A, Jefferies CA, Lawrenson K, Chan JL, Joshi NV, Zhu Y, Tseng HR, Wang ET, Ishimori M, Karumanchi SA, Williams J 3rd, Pisarska MD. Flowers AE, et al. Among authors: wang et. Placenta. 2024 May;150:8-21. doi: 10.1016/j.placenta.2024.03.005. Epub 2024 Mar 21. Placenta. 2024. PMID: 38537412
327 results