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Discovery of a Novel Potent and Selective HSD17B13 Inhibitor, BI-3231, a Well-Characterized Chemical Probe Available for Open Science.
Thamm S, Willwacher MK, Aspnes GE, Bretschneider T, Brown NF, Buschbom-Helmke S, Fox T, Gargano EM, Grabowski D, Hoenke C, Matera D, Mueck K, Peters S, Reindl S, Riether D, Schmid M, Tautermann CS, Teitelbaum AM, Trünkle C, Veser T, Winter M, Wortmann L. Thamm S, et al. Among authors: winter m. J Med Chem. 2023 Feb 23;66(4):2832-2850. doi: 10.1021/acs.jmedchem.2c01884. Epub 2023 Feb 2. J Med Chem. 2023. PMID: 36727857 Free PMC article.
RapidFire BLAZE-Mode Is Boosting ESI-MS Toward High-Throughput-Screening.
Bretschneider T, Ozbal C, Holstein M, Winter M, Buettner FH, Thamm S, Bischoff D, Luippold AH. Bretschneider T, et al. Among authors: winter m. SLAS Technol. 2019 Aug;24(4):386-393. doi: 10.1177/2472630318822449. Epub 2019 Jan 30. SLAS Technol. 2019. PMID: 30698995
MALDI-TOF-Based Affinity Selection Mass Spectrometry for Automated Screening of Protein-Ligand Interactions at High Throughput.
Simon RP, Winter M, Kleiner C, Wehrle L, Karnath M, Ries R, Zeeb M, Schnapp G, Fiegen D, Häbe TT, Runge F, Bretschneider T, Luippold AH, Bischoff D, Reindl W, Büttner FH. Simon RP, et al. Among authors: winter m. SLAS Discov. 2021 Jan;26(1):44-57. doi: 10.1177/2472555220959266. Epub 2020 Oct 17. SLAS Discov. 2021. PMID: 33073664 Free article.
Differential analyte derivatization enables unbiased MALDI-TOF-based high-throughput screening: A proof-of-concept study for the discovery of catechol-o-methyltransferase inhibitors.
Winter M, Simon RP, Wang Y, Bretschneider T, Bauer M, Magarkar A, Reindl W, Fernández-Montalván A, Montel F, Büttner FH. Winter M, et al. SLAS Discov. 2022 Jul;27(5):287-297. doi: 10.1016/j.slasd.2022.05.002. Epub 2022 May 18. SLAS Discov. 2022. PMID: 35597517 Free article.
1,914 results