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Lymphoid tissue-resident Alcaligenes LPS induces IgA production without excessive inflammatory responses via weak TLR4 agonist activity.
Shibata N, Kunisawa J, Hosomi K, Fujimoto Y, Mizote K, Kitayama N, Shimoyama A, Mimuro H, Sato S, Kishishita N, Ishii KJ, Fukase K, Kiyono H. Shibata N, et al. Among authors: shimoyama a. Mucosal Immunol. 2018 May;11(3):693-702. doi: 10.1038/mi.2017.103. Epub 2018 Feb 7. Mucosal Immunol. 2018. PMID: 29411777 Free article.
Adjuvant Activity of Synthetic Lipid A of Alcaligenes, a Gut-Associated Lymphoid Tissue-Resident Commensal Bacterium, to Augment Antigen-Specific IgG and Th17 Responses in Systemic Vaccine.
Wang Y, Hosomi K, Shimoyama A, Yoshii K, Yamaura H, Nagatake T, Nishino T, Kiyono H, Fukase K, Kunisawa J. Wang Y, et al. Among authors: shimoyama a. Vaccines (Basel). 2020 Jul 20;8(3):395. doi: 10.3390/vaccines8030395. Vaccines (Basel). 2020. PMID: 32698404 Free PMC article.
Chemically Synthesized Alcaligenes Lipid A Shows a Potent and Safe Nasal Vaccine Adjuvant Activity for the Induction of Streptococcus pneumoniae-Specific IgA and Th17 Mediated Protective Immunity.
Yoshii K, Hosomi K, Shimoyama A, Wang Y, Yamaura H, Nagatake T, Suzuki H, Lan H, Kiyono H, Fukase K, Kunisawa J. Yoshii K, et al. Among authors: shimoyama a. Microorganisms. 2020 Jul 23;8(8):1102. doi: 10.3390/microorganisms8081102. Microorganisms. 2020. PMID: 32718009 Free PMC article.
Lipopolysaccharide from Gut-Associated Lymphoid-Tissue-Resident Alcaligenes faecalis: Complete Structure Determination and Chemical Synthesis of Its Lipid A.
Shimoyama A, Di Lorenzo F, Yamaura H, Mizote K, Palmigiano A, Pither MD, Speciale I, Uto T, Masui S, Sturiale L, Garozzo D, Hosomi K, Shibata N, Kabayama K, Fujimoto Y, Silipo A, Kunisawa J, Kiyono H, Molinaro A, Fukase K. Shimoyama A, et al. Angew Chem Int Ed Engl. 2021 Apr 26;60(18):10023-10031. doi: 10.1002/anie.202012374. Epub 2021 Mar 22. Angew Chem Int Ed Engl. 2021. PMID: 33522128 Free PMC article.
72 results