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T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formation.
Landshammer A, Bolondi A, Kretzmer H, Much C, Buschow R, Rose A, Wu HJ, Mackowiak SD, Braendl B, Giesselmann P, Tornisiello R, Parsi KM, Huey J, Mielke T, Meierhofer D, Maehr R, Hnisz D, Michor F, Rinn JL, Meissner A. Landshammer A, et al. Among authors: mielke t. Elife. 2023 Jan 31;12:e83077. doi: 10.7554/eLife.83077. Elife. 2023. PMID: 36719724 Free PMC article.
Carbon ion radiotherapy of hepatocellular carcinoma provides excellent local control: The prospective phase I PROMETHEUS trial.
Hoegen-Saßmannshausen P, Naumann P, Hoffmeister-Wittmann P, Ben Harrabi S, Seidensaal K, Weykamp F, Mielke T, Ellerbrock M, Habermehl D, Springfeld C, Dill MT, Longerich T, Schirmacher P, Mehrabi A, Chang DH, Hörner-Rieber J, Jäkel O, Haberer T, Combs SE, Debus J, Herfarth K, Liermann J. Hoegen-Saßmannshausen P, et al. Among authors: mielke t. JHEP Rep. 2024 Mar 11;6(6):101063. doi: 10.1016/j.jhepr.2024.101063. eCollection 2024 Jun. JHEP Rep. 2024. PMID: 38737600 Free PMC article.
Regulatory Issues of Platform Trials: Learnings from EU-PEARL.
Nguyen QL, Hees K, Hernandez Penna S, König F, Posch M, Bofill Roig M, Meyer EL, Freitag MM, Parke T, Otte M, Dauben HP, Mielke T, Spiertz C, Mesenbrink P, Gidh-Jain M, Pierre S, Morello S, Hofner B. Nguyen QL, et al. Among authors: mielke t. Clin Pharmacol Ther. 2024 Mar 26. doi: 10.1002/cpt.3244. Online ahead of print. Clin Pharmacol Ther. 2024. PMID: 38529786 Review.
FOXO1-mediated lipid metabolism maintains mammalian embryos in dormancy.
van der Weijden VA, Stötzel M, Iyer DP, Fauler B, Gralinska E, Shahraz M, Meierhofer D, Vingron M, Rulands S, Alexandrov T, Mielke T, Bulut-Karslioglu A. van der Weijden VA, et al. Among authors: mielke t. Nat Cell Biol. 2024 Feb;26(2):181-193. doi: 10.1038/s41556-023-01325-3. Epub 2024 Jan 4. Nat Cell Biol. 2024. PMID: 38177284 Free PMC article.
A nanobody recognizes a unique conserved epitope and potently neutralizes SARS-CoV-2 omicron variants.
Modhiran N, Lauer SM, Amarilla AA, Hewins P, Lopes van den Broek SI, Low YS, Thakur N, Liang B, Nieto GV, Jung J, Paramitha D, Isaacs A, Sng JDJ, Song D, Jørgensen JT, Cheuquemilla Y, Bürger J, Andersen IV, Himelreichs J, Jara R, MacLoughlin R, Miranda-Chacon Z, Chana-Cuevas P, Kramer V, Spahn C, Mielke T, Khromykh AA, Munro T, Jones ML, Young PR, Chappell K, Bailey D, Kjaer A, Herth MM, Jurado KA, Schwefel D, Rojas-Fernandez A, Watterson D. Modhiran N, et al. Among authors: mielke t. iScience. 2023 Jun 9;26(7):107085. doi: 10.1016/j.isci.2023.107085. eCollection 2023 Jul 21. iScience. 2023. PMID: 37361875 Free PMC article.
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