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Hypermigration of macrophages through the concerted action of GRA effectors on NF-κB/p38 signaling and host chromatin accessibility potentiates Toxoplasma dissemination.
Ten Hoeve AL, Rodriguez ME, Säflund M, Michel V, Magimel L, Ripoll A, Yu T, Hakimi MA, Saeij JPJ, Ozata DM, Barragan A. Ten Hoeve AL, et al. Among authors: hakimi ma. bioRxiv [Preprint]. 2024 Feb 6:2024.02.06.579146. doi: 10.1101/2024.02.06.579146. bioRxiv. 2024. PMID: 38370679 Free PMC article. Preprint.
In vitro production of cat-restricted Toxoplasma pre-sexual stages.
Antunes AV, Shahinas M, Swale C, Farhat DC, Ramakrishnan C, Bruley C, Cannella D, Robert MG, Corrao C, Couté Y, Hehl AB, Bougdour A, Coppens I, Hakimi MA. Antunes AV, et al. Among authors: hakimi ma. Nature. 2024 Jan;625(7994):366-376. doi: 10.1038/s41586-023-06821-y. Epub 2023 Dec 13. Nature. 2024. PMID: 38093015 Free PMC article.
The Toxoplasma effector GRA28 promotes parasite dissemination by inducing dendritic cell-like migratory properties in infected macrophages.
Ten Hoeve AL, Braun L, Rodriguez ME, Olivera GC, Bougdour A, Belmudes L, Couté Y, Saeij JPJ, Hakimi MA, Barragan A. Ten Hoeve AL, et al. Among authors: hakimi ma. Cell Host Microbe. 2022 Nov 9;30(11):1570-1588.e7. doi: 10.1016/j.chom.2022.10.001. Epub 2022 Oct 28. Cell Host Microbe. 2022. PMID: 36309013 Free PMC article.
Altiratinib blocks Toxoplasma gondii and Plasmodium falciparum development by selectively targeting a spliceosome kinase.
Swale C, Bellini V, Bowler MW, Flore N, Brenier-Pinchart MP, Cannella D, Belmudes L, Mas C, Couté Y, Laurent F, Scherf A, Bougdour A, Hakimi MA. Swale C, et al. Among authors: hakimi ma. Sci Transl Med. 2022 Aug 3;14(656):eabn3231. doi: 10.1126/scitranslmed.abn3231. Epub 2022 Aug 3. Sci Transl Med. 2022. PMID: 35921477 Free article.
86 results