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Deoxycytidine kinase (dCK) inhibition is synthetic lethal with BRCA2 deficiency.
Guantay L, Garro C, Siri S, Pansa MF, Ghidelli-Disse S, Paviolo N, Racca A, Nicotra V, Radu C, Bocco JL, Felice R, Jansson KH, Remlinger K, Amador A, Stronach E, Coleman K, Muelbaier M, Drewes G, Gloger I, Madauss K, García M, Gottifredi V, Soria G. Guantay L, et al. Among authors: racca a. Drug Resist Updat. 2023 Mar;67:100932. doi: 10.1016/j.drup.2023.100932. Epub 2023 Jan 22. Drug Resist Updat. 2023. PMID: 36706533
Polo-like Kinase 1 Inhibition as a Therapeutic Approach to Selectively Target BRCA1-Deficient Cancer Cells by Synthetic Lethality Induction.
Carbajosa S, Pansa MF, Paviolo NS, Castellaro AM, Andino DL, Nigra AD, García IA, Racca AC, Rodriguez-Berdini L, Angiolini V, Guantay L, Villafañez F, Federico MB, Rodríguez-Baili MC, Caputto BL, Drewes G, Madauss KP, Gloger I, Fernandez E, Gil GA, Bocco JL, Gottifredi V, Soria G. Carbajosa S, et al. Among authors: racca ac. Clin Cancer Res. 2019 Jul 1;25(13):4049-4062. doi: 10.1158/1078-0432.CCR-18-3516. Epub 2019 Mar 19. Clin Cancer Res. 2019. PMID: 30890549
StarD7 deficiency hinders cell motility through p-ERK1/2/Cx43 reduction.
Cruz Del Puerto M, Rojas ML, Racca AC, Kourdova LT, Miranda AL, Panzetta-Dutari G, Genti-Raimondi S, Flores-Martín JB. Cruz Del Puerto M, et al. PLoS One. 2022 Dec 30;17(12):e0279912. doi: 10.1371/journal.pone.0279912. eCollection 2022. PLoS One. 2022. PMID: 36584213 Free PMC article.
Role of the lipid transport protein StarD7 in mitochondrial dynamics.
Rojas ML, Cruz Del Puerto MM, Flores-Martín J, Racca AC, Kourdova LT, Miranda AL, Panzetta-Dutari GM, Genti-Raimondi S. Rojas ML, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2021 Dec;1866(12):159029. doi: 10.1016/j.bbalip.2021.159029. Epub 2021 Aug 17. Biochim Biophys Acta Mol Cell Biol Lipids. 2021. PMID: 34416390
150 results