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Diversity-oriented synthesis of glycomimetics.
Meanwell M, Fehr G, Ren W, Adluri B, Rose V, Lehmann J, Silverman SM, Rowshanpour R, Adamson C, Bergeron-Brlek M, Foy H, Challa VR, Campeau LC, Dudding T, Britton R. Meanwell M, et al. Among authors: bergeron brlek m. Commun Chem. 2021 Jun 24;4(1):96. doi: 10.1038/s42004-021-00520-3. Commun Chem. 2021. PMID: 36697548 Free PMC article.
Thiol-to-amine cyclization reaction enables screening of large libraries of macrocyclic compounds and the generation of sub-kilodalton ligands.
Kale SS, Bergeron-Brlek M, Wu Y, Kumar MG, Pham MV, Bortoli J, Vesin J, Kong XD, Machado JF, Deyle K, Gonschorek P, Turcatti G, Cendron L, Angelini A, Heinis C. Kale SS, et al. Among authors: bergeron brlek m. Sci Adv. 2019 Aug 21;5(8):eaaw2851. doi: 10.1126/sciadv.aaw2851. eCollection 2019 Aug. Sci Adv. 2019. PMID: 31457083 Free PMC article.
Cyclols Revisited: Facile Synthesis of Medium-Sized Cyclic Peptides.
Mendoza-Sanchez R, Corless VB, Nguyen QNN, Bergeron-Brlek M, Frost J, Adachi S, Tantillo DJ, Yudin AK. Mendoza-Sanchez R, et al. Among authors: bergeron brlek m. Chemistry. 2017 Sep 27;23(54):13319-13322. doi: 10.1002/chem.201703616. Epub 2017 Aug 31. Chemistry. 2017. PMID: 28771904
Modular synthesis of amphiphilic Janus glycodendrimers and their self-assembly into glycodendrimersomes and other complex architectures with bioactivity to biomedically relevant lectins.
Percec V, Leowanawat P, Sun HJ, Kulikov O, Nusbaum CD, Tran TM, Bertin A, Wilson DA, Peterca M, Zhang S, Kamat NP, Vargo K, Moock D, Johnston ED, Hammer DA, Pochan DJ, Chen Y, Chabre YM, Shiao TC, Bergeron-Brlek M, André S, Roy R, Gabius HJ, Heiney PA. Percec V, et al. Among authors: bergeron brlek m. J Am Chem Soc. 2013 Jun 19;135(24):9055-77. doi: 10.1021/ja403323y. Epub 2013 Jun 6. J Am Chem Soc. 2013. PMID: 23692629