Hirabayashi H - Search Results

1

Preferential delivery of lipid-ligand conjugated DNA/RNA heteroduplex oligonucleotide to ischemic brain in hyperacute stage.

Li F, Ichinose K, Ishibashi S, Yamamoto S, Iwasawa E, Suzuki M, Yoshida-Tanaka K, Yoshioka K, Nagata T, Hirabayashi H, Mogushi K, Yokota T. Li F, et al. Among authors: hirabayashi h. Mol Ther. 2023 Apr 5;31(4):1106-1122. doi: 10.1016/j.ymthe.2023.01.016. Epub 2023 Jan 24. Mol Ther. 2023. PMID: 36694463 Free PMC article.

2

Utility of Göttingen minipigs for Prediction of Human Pharmacokinetic Profiles After Dermal Drug Application.

Yamamoto S, Karashima M, Sano N, Fukushi C, Tohyama K, Arai Y, Hirabayashi H, Amano N. Yamamoto S, et al. Among authors: hirabayashi h. Pharm Res. 2017 Nov;34(11):2415-2424. doi: 10.1007/s11095-017-2247-7. Epub 2017 Aug 21. Pharm Res. 2017. PMID: 28828717

3

Impact of P-Glycoprotein on Intestinal Absorption of an Inhibitor of Apoptosis Protein Antagonist in Rats: Mechanisms of Nonlinear Pharmacokinetics and Food Effects.

Yamamoto S, Kosugi Y, Hirabayashi H, Moriwaki T. Yamamoto S, et al. Among authors: hirabayashi h. Pharm Res. 2018 Aug 13;35(10):190. doi: 10.1007/s11095-018-2470-x. Pharm Res. 2018. PMID: 30105478

4

Direct Drug Delivery of Low-Permeable Compounds to the Central Nervous System Via Intranasal Administration in Rats and Monkeys.

Iwasaki S, Yamamoto S, Sano N, Tohyama K, Kosugi Y, Furuta A, Hamada T, Igari T, Fujioka Y, Hirabayashi H, Amano N. Iwasaki S, et al. Among authors: hirabayashi h. Pharm Res. 2019 Apr 1;36(5):76. doi: 10.1007/s11095-019-2613-8. Pharm Res. 2019. PMID: 30937626

5

Utility of hairless rats as a model for predicting transdermal pharmacokinetics in humans.

Yamamoto S, Sano N, Fukushi C, Arai Y, Karashima M, Hirabayashi H, Amano N. Yamamoto S, et al. Among authors: hirabayashi h. Xenobiotica. 2020 Jul;50(7):831-838. doi: 10.1080/00498254.2019.1703059. Epub 2019 Dec 17. Xenobiotica. 2020. PMID: 31814485

6

Quantitative application of flow cytometry for the analysis of circulating human T cells: A preclinical pharmacokinetic study.

Yamamoto S, Matsumoto SI, Shimizu H, Hirabayashi H. Yamamoto S, et al. Among authors: hirabayashi h. Drug Metab Pharmacokinet. 2020 Apr;35(2):207-213. doi: 10.1016/j.dmpk.2019.11.003. Epub 2019 Dec 21. Drug Metab Pharmacokinet. 2020. PMID: 31980378

7

Quantitative PCR methodology with a volume-based unit for the sophisticated cellular kinetic evaluation of chimeric antigen receptor T cells.

Yamamoto S, Matsumoto SI, Goto A, Ugajin M, Nakayama M, Moriya Y, Hirabayashi H. Yamamoto S, et al. Among authors: hirabayashi h. Sci Rep. 2020 Oct 21;10(1):17884. doi: 10.1038/s41598-020-74927-8. Sci Rep. 2020. PMID: 33087808 Free PMC article.

8

Highly specific, quantitative polymerase chain reaction probe for the quantification of human cells in cynomolgus monkeys.

Yamamoto S, Ding N, Matsumoto SI, Hirabayashi H. Yamamoto S, et al. Among authors: hirabayashi h. Drug Metab Pharmacokinet. 2021 Feb;36:100359. doi: 10.1016/j.dmpk.2020.09.004. Epub 2020 Sep 28. Drug Metab Pharmacokinet. 2021. PMID: 33348238 Free article.

9

Development of a bioanalytical method for circulating human T cells in animals using Arthrobacter luteus-based quantitative polymerase chain reaction and its application in preclinical biodistribution studies.

Shimizu H, Kuze Y, Higuchi T, Matsumoto SI, Yamamoto S, Goto A, Moriya Y, Hirabayashi H. Shimizu H, et al. Among authors: hirabayashi h. Regen Ther. 2020 Nov 17;15:251-257. doi: 10.1016/j.reth.2020.10.003. eCollection 2020 Dec. Regen Ther. 2020. PMID: 33426226 Free PMC article.

10

Cholesterol-functionalized DNA/RNA heteroduplexes cross the blood-brain barrier and knock down genes in the rodent CNS.

Nagata T, Dwyer CA, Yoshida-Tanaka K, Ihara K, Ohyagi M, Kaburagi H, Miyata H, Ebihara S, Yoshioka K, Ishii T, Miyata K, Miyata K, Powers B, Igari T, Yamamoto S, Arimura N, Hirabayashi H, Uchihara T, Hara RI, Wada T, Bennett CF, Seth PP, Rigo F, Yokota T. Nagata T, et al. Among authors: hirabayashi h. Nat Biotechnol. 2021 Dec;39(12):1529-1536. doi: 10.1038/s41587-021-00972-x. Epub 2021 Aug 12. Nat Biotechnol. 2021. PMID: 34385691

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