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Structures of Pseudomonas aeruginosa β-ketoacyl-(acyl-carrier-protein) synthase II (FabF) and a C164Q mutant provide templates for antibacterial drug discovery and identify a buried potassium ion and a ligand-binding site that is an artefact of the crystal form.
Baum B, Lecker LS, Zoltner M, Jaenicke E, Schnell R, Hunter WN, Brenk R. Baum B, et al. Among authors: zoltner m. Acta Crystallogr F Struct Biol Commun. 2015 Aug;71(Pt 8):1020-6. doi: 10.1107/S2053230X15010614. Epub 2015 Jul 28. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 26249693 Free PMC article.
Heterogeneity in ess transcriptional organization and variable contribution of the Ess/Type VII protein secretion system to virulence across closely related Staphylocccus aureus strains.
Kneuper H, Cao ZP, Twomey KB, Zoltner M, Jäger F, Cargill JS, Chalmers J, van der Kooi-Pol MM, van Dijl JM, Ryan RP, Hunter WN, Palmer T. Kneuper H, et al. Among authors: zoltner m. Mol Microbiol. 2014 Sep;93(5):928-43. doi: 10.1111/mmi.12707. Epub 2014 Jul 30. Mol Microbiol. 2014. PMID: 25040609 Free PMC article.
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