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Chemically diverse activity-based probes with unexpected inhibitory mechanisms targeting trypsin-like serine proteases.
Front Chem. 2023 Jan 5;10:1089959. doi: 10.3389/fchem.2022.1089959. eCollection 2022.
Front Chem. 2023.
PMID: 36688031
Free PMC article.
The Potential Role of Regulated Cell Death in Dry Eye Diseases and Ocular Surface Dysfunction.
Scarpellini C, Ramos Llorca A, Lanthier C, Klejborowska G, Augustyns K.
Scarpellini C, et al. Among authors: ramos llorca a.
Int J Mol Sci. 2023 Jan 1;24(1):731. doi: 10.3390/ijms24010731.
Int J Mol Sci. 2023.
PMID: 36614174
Free PMC article.
Review.
Item in Clipboard
Improved Synthesis of the Selected Serine Protease uPA Inhibitor UAMC-00050, a Lead Compound for the Treatment of Dry Eye Disease.
Ceradini D, Cacivkins P, Ramos-Llorca A, Shubin K.
Ceradini D, et al. Among authors: ramos llorca a.
Org Process Res Dev. 2022 Oct 21;26(10):2937-2946. doi: 10.1021/acs.oprd.2c00244. Epub 2022 Sep 30.
Org Process Res Dev. 2022.
PMID: 36311379
Free PMC article.
Review.
Item in Clipboard
Proteases and Their Potential Role as Biomarkers and Drug Targets in Dry Eye Disease and Ocular Surface Dysfunction.
Ramos-Llorca A, Scarpellini C, Augustyns K.
Ramos-Llorca A, et al.
Int J Mol Sci. 2022 Aug 29;23(17):9795. doi: 10.3390/ijms23179795.
Int J Mol Sci. 2022.
PMID: 36077189
Free PMC article.
Review.
Item in Clipboard
Identification of Phenylpyrazolone Dimers as a New Class of Anti-Trypanosoma cruzi Agents.
Sijm M, Siciliano de Araújo J, Ramos Llorca A, Orrling K, Stiny L, Matheeussen A, Maes L, de Esch IJP, de Nazaré Correia Soeiro M, Sterk GJ, Leurs R.
Sijm M, et al. Among authors: ramos llorca a.
ChemMedChem. 2019 Sep 18;14(18):1662-1668. doi: 10.1002/cmdc.201900370. Epub 2019 Aug 23.
ChemMedChem. 2019.
PMID: 31319019
Free PMC article.
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