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Potent SARS-CoV-2 mRNA Cap Methyltransferase Inhibitors by Bioisosteric Replacement of Methionine in SAM Cosubstrate.
Bobiļeva O, Bobrovs R, Kaņepe I, Patetko L, Kalniņš G, Šišovs M, Bula AL, Gri Nberga S, Borodušķis MR, Ramata-Stunda A, Rostoks N, Jirgensons A, Ta Rs K, Jaudzems K. Bobiļeva O, et al. ACS Med Chem Lett. 2021 Jun 9;12(7):1102-1107. doi: 10.1021/acsmedchemlett.1c00140. eCollection 2021 Jul 8. ACS Med Chem Lett. 2021. PMID: 34257831 Free PMC article.
Macrocyclic Peptidomimetic Plasmepsin X Inhibitors with Potent In Vitro and In Vivo Antimalarial Activity.
Kovada V, Withers-Martinez C, Bobrovs R, Ce Rule HN, Liepins E, Grinberga S, Hackett F, Collins CR, Kreicberga A, Jiménez-Díaz MB, Angulo-Barturen I, Rasina D, Suna E, Jaudzems K, Blackman MJ, Jirgensons A. Kovada V, et al. Among authors: grinberga s. J Med Chem. 2023 Aug 10;66(15):10658-10680. doi: 10.1021/acs.jmedchem.3c00812. Epub 2023 Jul 28. J Med Chem. 2023. PMID: 37505188 Free PMC article.
Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria.
Huseby DL, Cao S, Zamaratski E, Sooriyaarachchi S, Ahmad S, Bergfors T, Krasnova L, Pelss J, Ikaunieks M, Loza E, Katkevics M, Bobileva O, Cirule H, Gukalova B, Grinberga S, Backlund M, Simoff I, Leber AT, Berruga-Fernández T, Antonov D, Konda VR, Lindström S, Olanders G, Brandt P, Baranczewski P, Vingsbo Lundberg C, Liepinsh E, Suna E, Jones TA, Mowbray SL, Hughes D, Karlén A. Huseby DL, et al. Among authors: grinberga s. Proc Natl Acad Sci U S A. 2024 Apr 9;121(15):e2317274121. doi: 10.1073/pnas.2317274121. Epub 2024 Apr 5. Proc Natl Acad Sci U S A. 2024. PMID: 38579010 Free PMC article.
Efficacy of Proanthocyanidins from Pelargonium sidoides Root Extract in Reducing P. gingivalis Viability While Preserving Oral Commensal S. salivarius.
Savickiene N, Jekabsone A, Raudone L, Abdelgeliel AS, Cochis A, Rimondini L, Makarova E, Grinberga S, Pugovics O, Dambrova M, Pacauskiene IM, Basevičiene N, Viškelis P. Savickiene N, et al. Among authors: grinberga s. Materials (Basel). 2018 Aug 22;11(9):1499. doi: 10.3390/ma11091499. Materials (Basel). 2018. PMID: 30135370 Free PMC article.
Excretion of the Polymyxin Derivative NAB739 in Murine Urine.
Vaara M, Vaara T, Kuka J, Sevostjanovs E, Grinberga S, Dambrova M, Liepinsh E. Vaara M, et al. Among authors: grinberga s. Antibiotics (Basel). 2020 Mar 27;9(4):143. doi: 10.3390/antibiotics9040143. Antibiotics (Basel). 2020. PMID: 32230751 Free PMC article.
The Association of Circulating L-Carnitine, γ-Butyrobetaine and Trimethylamine N-Oxide Levels with Gastric Cancer.
Stonāns I, Kuzmina J, Poļaka I, Grīnberga S, Sevostjanovs E, Liepiņš E, Aleksandraviča I, Šantare D, Kiršners A, Škapars R, Pčolkins A, Tolmanis I, Sīviņš A, Leja M, Dambrova M. Stonāns I, et al. Among authors: grinberga s. Diagnostics (Basel). 2023 Apr 4;13(7):1341. doi: 10.3390/diagnostics13071341. Diagnostics (Basel). 2023. PMID: 37046558 Free PMC article.
68 results