Pacheco PAF - Search Results

1

Synthesis, Biological Evaluation and Molecular Modeling Studies of Naphthoquinone Sulfonamides and Sulfonate Ester Derivatives as P2X7 Inhibitors.

Pacheco PAF, Gonzaga DTG, von Ranke NL, Rodrigues CR, da Rocha DR, da Silva FC, Ferreira VF, Faria RX. Pacheco PAF, et al. Molecules. 2023 Jan 6;28(2):590. doi: 10.3390/molecules28020590. Molecules. 2023. PMID: 36677652 Free PMC article.

2

Modulation of P2 receptors on pancreatic β-cells by agonists and antagonists: a molecular target for type 2 diabetes treatment.

Pacheco PA, Ferreira LG, Alves LA, Faria RX. Pacheco PA, et al. Curr Diabetes Rev. 2013 May;9(3):228-36. doi: 10.2174/1573399811309030004. Curr Diabetes Rev. 2013. PMID: 23506378 Review.

3

P2X7 receptor as a novel drug delivery system to increase the entrance of hydrophilic drugs into cells during photodynamic therapy.

Pacheco PA, Ferreira LB, Mendonça L, Ferreira DN, Salles JP, Faria RX, Teixeira PC, Alves LA. Pacheco PA, et al. J Bioenerg Biomembr. 2016 Aug;48(4):397-411. doi: 10.1007/s10863-016-9668-6. Epub 2016 Jul 15. J Bioenerg Biomembr. 2016. PMID: 27422545

4

Searching for new drugs for Chagas diseases: triazole analogs display high in vitro activity against Trypanosoma cruzi and low toxicity toward mammalian cells.

Faria RX, Gonzaga DTG, Pacheco PAF, Souza ALA, Ferreira VF, da Silva FC. Faria RX, et al. Among authors: pacheco paf. J Bioenerg Biomembr. 2018 Apr;50(2):81-91. doi: 10.1007/s10863-018-9746-z. Epub 2018 Feb 23. J Bioenerg Biomembr. 2018. PMID: 29473131

5

Synthesis of new N,S-acetal analogs derived from juglone with cytotoxic activity against Trypanossoma cruzi.

Pacheco PAF, de Menezes Ribeiro T, Dos Santos Galvão RM, Dos Santos EG, Faria AFM, von Ranke NL, Bello ML, Rodrigues CR, Ferreira VF, Souza ALA, de Jesús Hardoim D, da Silva Calabrese K, Faria RX, da Rocha DR. Pacheco PAF, et al. J Bioenerg Biomembr. 2020 Jun;52(3):199-213. doi: 10.1007/s10863-020-09834-8. Epub 2020 May 17. J Bioenerg Biomembr. 2020. PMID: 32418003

6

Plant natural products as source of new P2 receptors ligands.

Pacheco PAF, Diogo RT, Magalhães BQ, Faria RX. Pacheco PAF, et al. Fitoterapia. 2020 Oct;146:104709. doi: 10.1016/j.fitote.2020.104709. Epub 2020 Aug 20. Fitoterapia. 2020. PMID: 32829014 Review.

7

Semisynthetic triterpenes led to the generation of selective antitrypanosomal lead compounds.

Guilhon-Simplicio F, Serrão CKR, Pinto ACDS, Pacheco PAF, Faria RX, da Rocha DR, Ferreira VF, Pereira-Junior RC, Matheeussen A, Baán A, Kiekens F, de Meneses Pereira M, Lima ES, Winter H, Cos P. Guilhon-Simplicio F, et al. Among authors: pacheco paf. Chem Biol Drug Des. 2022 Jun;99(6):868-883. doi: 10.1111/cbdd.14040. Epub 2022 Mar 31. Chem Biol Drug Des. 2022. PMID: 35313075

8

In silico and pharmacological study of N,S-acetal juglone derivatives as inhibitors of the P2X7 receptor-promoted in vitro and in vivo inflammatory response.

Pacheco PAF, Faria JV, Silva AC, von Ranke NL, Silva RC, Rodrigues CR, da Rocha DR, Faria RX. Pacheco PAF, et al. Biomed Pharmacother. 2023 Jun;162:114608. doi: 10.1016/j.biopha.2023.114608. Epub 2023 Mar 30. Biomed Pharmacother. 2023. PMID: 37003033 Free article.

9

Naphthoquinones as a Promising Class of Compounds for Facing the Challenge of Parkinson's Disease.

Santos TB, de Moraes LGC, Pacheco PAF, Dos Santos DG, Ribeiro RMAC, Moreira CDS, da Rocha DR. Santos TB, et al. Among authors: pacheco paf. Pharmaceuticals (Basel). 2023 Nov 8;16(11):1577. doi: 10.3390/ph16111577. Pharmaceuticals (Basel). 2023. PMID: 38004442 Free PMC article. Review.

10

New Strategies for Acute Liver Failure: Focus on Xenotransplantation Therapy.

Alves LA, Bonavita A, Quaresma K, Torres E, Pacheco PA, Cotta-de-Almeida V, Saraiva RM. Alves LA, et al. Cell Med. 2010 Jul 1;1(1):47-54. doi: 10.3727/215517910X516646. eCollection 2010. Cell Med. 2010. PMID: 26998396 Free PMC article.

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