Huang HS - Search Results

1

Preclinical Evaluation of a Novel Small Molecule LCC-21 to Suppress Colorectal Cancer Malignancy by Inhibiting Angiogenic and Metastatic Signatures.

Mokgautsi N, Kuo YC, Huang YJ, Chen CH, Mukhopadhyay D, Wu ATH, Huang HS. Mokgautsi N, et al. Among authors: huang yj, huang hs. Cells. 2023 Jan 9;12(2):266. doi: 10.3390/cells12020266. Cells. 2023. PMID: 36672201 Free PMC article.

2

Identification and preclinical evaluation of the small molecule, NSC745887, for treating glioblastomas via suppressing DcR3-associated signaling pathways.

Fann LY, Chen Y, Chu DC, Weng SJ, Chu HC, Wu ATH, Lee JF, Ali AAA, Chen TC, Huang HS, Ma KH. Fann LY, et al. Among authors: huang hs. Oncotarget. 2017 Dec 27;9(15):11922-11937. doi: 10.18632/oncotarget.23714. eCollection 2018 Feb 23. Oncotarget. 2017. PMID: 29552282 Free PMC article.

3

A Novel Multi-Target Small Molecule, LCC-09, Inhibits Stemness and Therapy-Resistant Phenotypes of Glioblastoma Cells by Increasing miR-34a and Deregulating the DRD4/Akt/mTOR Signaling Axis.

Wen YT, Wu AT, Bamodu OA, Wei L, Lin CM, Yen Y, Chao TY, Mukhopadhyay D, Hsiao M, Huang HS. Wen YT, et al. Among authors: huang hs. Cancers (Basel). 2019 Sep 26;11(10):1442. doi: 10.3390/cancers11101442. Cancers (Basel). 2019. PMID: 31561595 Free PMC article.

4

Design and Evaluation of PEGylated Liposomal Formulation of a Novel Multikinase Inhibitor for Enhanced Chemosensitivity and Inhibition of Metastatic Pancreatic Ductal Adenocarcinoma.

Madamsetty VS, Pal K, Dutta SK, Wang E, Thompson JR, Banerjee RK, Caulfield TR, Mody K, Yen Y, Mukhopadhyay D, Huang HS. Madamsetty VS, et al. Among authors: huang hs. Bioconjug Chem. 2019 Oct 16;30(10):2703-2713. doi: 10.1021/acs.bioconjchem.9b00632. Epub 2019 Oct 4. Bioconjug Chem. 2019. PMID: 31584260

5

Preclinical Evaluation of the Novel Small-Molecule MSI-N1014 for Treating Drug-Resistant Colon Cancer via the LGR5/β-catenin/miR-142-3p Network and Reducing Cancer-Associated Fibroblast Transformation.

Yadav VK, Huang YJ, George TA, Wei PL, Sumitra MR, Ho CL, Chang TH, Wu ATH, Huang HS. Yadav VK, et al. Among authors: huang yj, huang hs. Cancers (Basel). 2020 Jun 16;12(6):1590. doi: 10.3390/cancers12061590. Cancers (Basel). 2020. PMID: 32560222 Free PMC article.

6

HNC0014, a Multi-Targeted Small-Molecule, Inhibits Head and Neck Squamous Cell Carcinoma by Suppressing c-Met/STAT3/CD44/PD-L1 Oncoimmune Signature and Eliciting Antitumor Immune Responses.

Lee JC, Wu ATH, Chen JH, Huang WY, Lawal B, Mokgautsi N, Huang HS, Ho CL. Lee JC, et al. Among authors: huang wy, huang hs. Cancers (Basel). 2020 Dec 14;12(12):3759. doi: 10.3390/cancers12123759. Cancers (Basel). 2020. PMID: 33327484 Free PMC article.

7

LCC18, a benzamide-linked small molecule, ameliorates IgA nephropathy in mice.

Yang SR, Hua KF, Takahata A, Wu CY, Hsieh CY, Chiu HW, Chen CH, Mukhopadhyay D, Suzuki Y, Ka SM, Huang HS, Chen A. Yang SR, et al. Among authors: huang hs. J Pathol. 2021 Apr;253(4):427-441. doi: 10.1002/path.5609. Epub 2021 Jan 27. J Pathol. 2021. PMID: 33373038

8

Pharmacoinformatics and Preclinical Studies of NSC765690 and NSC765599, Potential STAT3/CDK2/4/6 Inhibitors with Antitumor Activities against NCI60 Human Tumor Cell Lines.

Lawal B, Liu YL, Mokgautsi N, Khedkar H, Sumitra MR, Wu ATH, Huang HS. Lawal B, et al. Among authors: huang hs. Biomedicines. 2021 Jan 19;9(1):92. doi: 10.3390/biomedicines9010092. Biomedicines. 2021. PMID: 33477856 Free PMC article.

9

An Integrated Bioinformatics Study of a Novel Niclosamide Derivative, NSC765689, a Potential GSK3β/β-Catenin/STAT3/CD44 Suppressor with Anti-Glioblastoma Properties.

Mokgautsi N, Wen YT, Lawal B, Khedkar H, Sumitra MR, Wu ATH, Huang HS. Mokgautsi N, et al. Among authors: huang hs. Int J Mol Sci. 2021 Feb 28;22(5):2464. doi: 10.3390/ijms22052464. Int J Mol Sci. 2021. PMID: 33671112 Free PMC article.

10

mTOR/EGFR/iNOS/MAP2K1/FGFR/TGFB1 Are Druggable Candidates for N-(2,4-Difluorophenyl)-2',4'-Difluoro-4-Hydroxybiphenyl-3-Carboxamide (NSC765598), With Consequent Anticancer Implications.

Lawal B, Lee CY, Mokgautsi N, Sumitra MR, Khedkar H, Wu ATH, Huang HS. Lawal B, et al. Among authors: huang hs. Front Oncol. 2021 Mar 26;11:656738. doi: 10.3389/fonc.2021.656738. eCollection 2021. Front Oncol. 2021. PMID: 33842373 Free PMC article.

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