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Discovery of benzochromene derivatives first example with dual cytotoxic activity against the resistant cancer cell MCF-7/ADR and inhibitory effect of the P-glycoprotein expression levels.
Al-Harbi LM, Al-Harbi EA, Okasha RM, El-Eisawy RA, El-Nassag MAA, Mohamed HM, Fouda AM, Elhenawy AA, Mora A, El-Agrody AM, El-Mawgoud HKA. Al-Harbi LM, et al. Among authors: mohamed hm. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2155814. doi: 10.1080/14756366.2022.2155814. J Enzyme Inhib Med Chem. 2023. PMID: 36662632 Free PMC article.
Antiproliferative effect, cell cycle arrest and apoptosis generation of novel synthesized anticancer heterocyclic derivatives based 4H-benzo[h]chromene.
Alblewi FF, Okasha RM, Hritani ZM, Mohamed HM, El-Nassag MAA, Halawa AH, Mora A, Fouda AM, Assiri MA, Al-Dies AM, Afifi TH, El-Agrody AM. Alblewi FF, et al. Among authors: mohamed hm. Bioorg Chem. 2019 Jun;87:560-571. doi: 10.1016/j.bioorg.2019.03.059. Epub 2019 Mar 22. Bioorg Chem. 2019. PMID: 30928878
Novel molecular discovery of promising amidine-based thiazole analogues as potent dual Matrix Metalloproteinase-2 and 9 inhibitors: Anticancer activity data with prominent cell cycle arrest and DNA fragmentation analysis effects.
Omar AM, Bajorath J, Ihmaid S, Mohamed HM, El-Agrody AM, Mora A, El-Araby ME, Ahmed HEA. Omar AM, et al. Among authors: mohamed hm. Bioorg Chem. 2020 Aug;101:103992. doi: 10.1016/j.bioorg.2020.103992. Epub 2020 Jun 2. Bioorg Chem. 2020. PMID: 32554279
Design, synthesis and bioactivity study on oxygen-heterocyclic-based pyran analogues as effective P-glycoprotein-mediated multidrug resistance in MCF-7/ADR cell.
Abd El-Wahab AHF, Borik RMA, Al-Dies AM, Fouda AM, Mohamed HM, El-Eisawy RA, Mora A, El-Nassag MAA, Abd Elhady AM, Elhenawy AA, El-Agrody AM. Abd El-Wahab AHF, et al. Among authors: mohamed hm. Sci Rep. 2024 Mar 31;14(1):7589. doi: 10.1038/s41598-024-56197-w. Sci Rep. 2024. PMID: 38555345 Free PMC article.
107 results