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Discovery of benzochromene derivatives first example with dual cytotoxic activity against the resistant cancer cell MCF-7/ADR and inhibitory effect of the P-glycoprotein expression levels.
J Enzyme Inhib Med Chem. 2023 Dec;38(1):2155814. doi: 10.1080/14756366.2022.2155814.
J Enzyme Inhib Med Chem. 2023.
PMID: 36662632
Free PMC article.
Synthesis of 9-Hydroxy-1H-Benzo[f]chromene Derivatives with Effective Cytotoxic Activity on MCF7/ADR, P-Glycoprotein Inhibitors, Cell Cycle Arrest and Apoptosis Effects.
Albalawi FF, El-Nassag MAA, El-Eisawy RA, Mohamed MBI, Fouda AM, Afifi TH, Elhenawy AA, Mora A, El-Agrody AM, El-Mawgoud HKA.
Albalawi FF, et al. Among authors: el mawgoud hka.
Int J Mol Sci. 2022 Dec 20;24(1):49. doi: 10.3390/ijms24010049.
Int J Mol Sci. 2022.
PMID: 36613493
Free PMC article.
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Discovery of novel rigid analogs of 2-naphthol with potent anticancer activity through multi-target topoisomerase I & II and tyrosine kinase receptor EGFR & VEGFR-2 inhibition mechanism.
El-Mawgoud HKA, Fouda AM, El-Nassag MAA, Elhenawy AA, Alshahrani MY, El-Agrody AM.
El-Mawgoud HKA, et al.
Chem Biol Interact. 2022 Mar 1;355:109838. doi: 10.1016/j.cbi.2022.109838. Epub 2022 Feb 3.
Chem Biol Interact. 2022.
PMID: 35123995
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Synthesis of β-Enaminonitrile-Linked 8-Methoxy-1H-Benzo[f]Chromene Moieties and Analysis of Their Antitumor Mechanisms.
Elgaafary M, Fouda AM, Mohamed HM, Hamed A, El-Mawgoud HKA, Jin L, Ulrich J, Simmet T, Syrovets T, El-Agrody AM.
Elgaafary M, et al. Among authors: el mawgoud hka.
Front Chem. 2021 Nov 22;9:759148. doi: 10.3389/fchem.2021.759148. eCollection 2021.
Front Chem. 2021.
PMID: 34881224
Free PMC article.
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Synthesis, in-Vitro Cytotoxicity and Antimicrobial Evaluations of Some Novel Thiazole Based Heterocycles.
El-Mawgoud HKA.
El-Mawgoud HKA.
Chem Pharm Bull (Tokyo). 2019;67(12):1314-1323. doi: 10.1248/cpb.c19-00681.
Chem Pharm Bull (Tokyo). 2019.
PMID: 31787658
Free article.
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Uses of 2-(Thiophene-2-carbonylcarbamothioylthio)acetic Acid as a Good Synthon for Construction of Some New Thiazole and Annulated Thiazole Derivatives.
El-Mawgoud HKA, Atta-Allah SR, Hemdan MM.
El-Mawgoud HKA, et al.
Chem Pharm Bull (Tokyo). 2018;66(10):992-998. doi: 10.1248/cpb.c18-00482.
Chem Pharm Bull (Tokyo). 2018.
PMID: 30270245
Free article.
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