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Pyridoxamine reduces methylglyoxal and markers of glycation and endothelial dysfunction, but does not improve insulin sensitivity or vascular function in abdominally obese individuals: A randomized double-blind placebo-controlled trial.
Van den Eynde MDG, Houben AJHM, Scheijen JLJM, Linkens AMA, Niessen PM, Simons N, Hanssen NMJ, Kusters YHAM, Eussen SJMP, Miyata T, Stehouwer CDA, Schalkwijk CG. Van den Eynde MDG, et al. Among authors: miyata t. Diabetes Obes Metab. 2023 May;25(5):1280-1291. doi: 10.1111/dom.14977. Epub 2023 Feb 14. Diabetes Obes Metab. 2023. PMID: 36655410 Clinical Trial.
Hyperglycaemia-induced impairment of endothelium-dependent vasorelaxation in rat mesenteric arteries is mediated by intracellular methylglyoxal levels in a pathway dependent on oxidative stress.
Brouwers O, Niessen PM, Haenen G, Miyata T, Brownlee M, Stehouwer CD, De Mey JG, Schalkwijk CG. Brouwers O, et al. Among authors: miyata t. Diabetologia. 2010 May;53(5):989-1000. doi: 10.1007/s00125-010-1677-0. Epub 2010 Feb 26. Diabetologia. 2010. PMID: 20186387 Free PMC article.
Pyridoxamine prevents increased atherosclerosis by intermittent methylglyoxal spikes in the aortic arches of ApoE-/- mice.
Hanssen NMJ, Tikellis C, Pickering RJ, Dragoljevic D, Lee MKS, Block T, Scheijen JL, Wouters K, Miyata T, Cooper ME, Murphy AJ, Thomas MC, Schalkwijk CG. Hanssen NMJ, et al. Among authors: miyata t. Biomed Pharmacother. 2023 Feb;158:114211. doi: 10.1016/j.biopha.2022.114211. Epub 2023 Jan 3. Biomed Pharmacother. 2023. PMID: 36916437 Free article.
A rapid simultaneous antigen detection of Haemophilus influenzae and Streptococcus pneumoniae for predicting the prognosis of acute otitis media.
Kono M, Kamide Y, Tanaka T, Uno Y, Kanesada K, Suzuki C, Sawaki S, Kunimoto M, Kayama C, Suzuki K, Kudo F, Matsubara S, Sawada S, Goto Y, Uchizono A, Murakami D, Miyata T, Okamura N, Hotomi M. Kono M, et al. Among authors: miyata t. J Infect Chemother. 2024 May 21:S1341-321X(24)00138-7. doi: 10.1016/j.jiac.2024.05.006. Online ahead of print. J Infect Chemother. 2024. PMID: 38782238
2,195 results