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Page 1
Essential role of N-terminal SAM regions in STIM1 multimerization and function.
Sallinger M, Humer C, Ong HL, Narayanasamy S, Lin QT, Fahrner M, Grabmayr H, Berlansky S, Choi S, Schmidt T, Maltan L, Atzgerstorfer L, Niederwieser M, Frischauf I, Romanin C, Stathopulos PB, Ambudkar I, Leitner R, Bonhenry D, Schindl R. Sallinger M, et al. Among authors: grabmayr h. Proc Natl Acad Sci U S A. 2024 May 21;121(21):e2318874121. doi: 10.1073/pnas.2318874121. Epub 2024 May 16. Proc Natl Acad Sci U S A. 2024. PMID: 38753510
Photocrosslinking-induced CRAC channel-like Orai1 activation independent of STIM1.
Maltan L, Weiß S, Najjar H, Leopold M, Lindinger S, Höglinger C, Höbarth L, Sallinger M, Grabmayr H, Berlansky S, Krivic D, Hopl V, Blaimschein A, Fahrner M, Frischauf I, Tiffner A, Derler I. Maltan L, et al. Among authors: grabmayr h. Nat Commun. 2023 Mar 8;14(1):1286. doi: 10.1038/s41467-023-36458-4. Nat Commun. 2023. PMID: 36890174 Free PMC article.
A single amino acid deletion in the ER Ca2+ sensor STIM1 reverses the in vitro and in vivo effects of the Stormorken syndrome-causing R304W mutation.
Gamage TH, Grabmayr H, Horvath F, Fahrner M, Misceo D, Louch WE, Gunnes G, Pullisaar H, Reseland JE, Lyngstadaas SP, Holmgren A, Amundsen SS, Rathner P, Cerofolini L, Ravera E, Krobath H, Luchinat C, Renger T, Müller N, Romanin C, Frengen E. Gamage TH, et al. Among authors: grabmayr h. Sci Signal. 2023 Feb 7;16(771):eadd0509. doi: 10.1126/scisignal.add0509. Epub 2023 Feb 7. Sci Signal. 2023. PMID: 36749824
Swing-out opening of stromal interaction molecule 1.
Horvath F, Berlansky S, Maltan L, Grabmayr H, Fahrner M, Derler I, Romanin C, Renger T, Krobath H. Horvath F, et al. Among authors: grabmayr h. Protein Sci. 2023 Mar;32(3):e4571. doi: 10.1002/pro.4571. Protein Sci. 2023. PMID: 36691702 Free PMC article.
Activation mechanisms and structural dynamics of STIM proteins.
Sallinger M, Grabmayr H, Humer C, Bonhenry D, Romanin C, Schindl R, Derler I. Sallinger M, et al. Among authors: grabmayr h. J Physiol. 2024 Apr;602(8):1475-1507. doi: 10.1113/JP283828. Epub 2023 Feb 2. J Physiol. 2024. PMID: 36651592 Review.
Discovery of novel gating checkpoints in the Orai1 calcium channel by systematic analysis of constitutively active mutants of its paralogs and orthologs.
Augustynek B, Gyimesi G, Dernič J, Sallinger M, Albano G, Klesse GJ, Kandasamy P, Grabmayr H, Frischauf I, Fuster DG, Peinelt C, Hediger MA, Bhardwaj R. Augustynek B, et al. Among authors: grabmayr h. Cell Calcium. 2022 Jul;105:102616. doi: 10.1016/j.ceca.2022.102616. Epub 2022 Jun 22. Cell Calcium. 2022. PMID: 35792401 Free article.
Orai1 Boosts SK3 Channel Activation.
Tiffner A, Hopl V, Schober R, Sallinger M, Grabmayr H, Höglinger C, Fahrner M, Lunz V, Maltan L, Frischauf I, Krivic D, Bhardwaj R, Schindl R, Hediger MA, Derler I. Tiffner A, et al. Among authors: grabmayr h. Cancers (Basel). 2021 Dec 17;13(24):6357. doi: 10.3390/cancers13246357. Cancers (Basel). 2021. PMID: 34944977 Free PMC article.
23 results