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Characterization of BNT162b2 mRNA to Evaluate Risk of Off-Target Antigen Translation.
J Pharm Sci. 2023 May;112(5):1364-1371. doi: 10.1016/j.xphs.2023.01.007. Epub 2023 Jan 13.
J Pharm Sci. 2023.
PMID: 36642376
Free PMC article.
The Race to Develop the Pfizer-BioNTech COVID-19 Vaccine: From the Pharmaceutical Scientists' Perspective.
Lewis LM, Badkar AV, Cirelli D, Combs R, Lerch TF.
Lewis LM, et al.
J Pharm Sci. 2023 Mar;112(3):640-647. doi: 10.1016/j.xphs.2022.09.014. Epub 2022 Sep 18.
J Pharm Sci. 2023.
PMID: 36130677
Free PMC article.
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Oligonucleotide mapping via mass spectrometry to enable comprehensive primary structure characterization of an mRNA vaccine against SARS-CoV-2.
Gau BC, Dawdy AW, Wang HL, Bare B, Castaneda CH, Friese OV, Thompson MS, Lerch TF, Cirelli DJ, Rouse JC.
Gau BC, et al. Among authors: cirelli dj.
Sci Rep. 2023 Jun 3;13(1):9038. doi: 10.1038/s41598-023-36193-2.
Sci Rep. 2023.
PMID: 37270636
Free PMC article.
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Strategies for Setting Patient-Centric Commercial Specifications for Biotherapeutic Products.
Ruesch MN, Benetti L, Berkay E, Cirelli DJ, Frantz N, Gastens MH, Kelley WP, Kretsinger J, Lewis M, Novick S, Rellahan B, Pack L, Stroop CJM, Subashi A, Yin P, Zeng M, Stults J.
Ruesch MN, et al. Among authors: cirelli dj.
J Pharm Sci. 2021 Feb;110(2):771-784. doi: 10.1016/j.xphs.2020.09.048. Epub 2020 Oct 7.
J Pharm Sci. 2021.
PMID: 33035537
Free article.
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Characterization of FcγRIIIA effector cells used in in vitro ADCC bioassay: Comparison of primary NK cells with engineered NK-92 and Jurkat T cells.
Hsieh YT, Aggarwal P, Cirelli D, Gu L, Surowy T, Mozier NM.
Hsieh YT, et al.
J Immunol Methods. 2017 Feb;441:56-66. doi: 10.1016/j.jim.2016.12.002. Epub 2016 Dec 8.
J Immunol Methods. 2017.
PMID: 27939300
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Rational optimization of a monoclonal antibody for simultaneous improvements in its solution properties and biological activity.
Kumar S, Roffi K, Tomar DS, Cirelli D, Luksha N, Meyer D, Mitchell J, Allen MJ, Li L.
Kumar S, et al.
Protein Eng Des Sel. 2018 Jul 1;31(7-8):313-325. doi: 10.1093/protein/gzy020.
Protein Eng Des Sel. 2018.
PMID: 30189027
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Establishing in vitro in vivo correlations to screen monoclonal antibodies for physicochemical properties related to favorable human pharmacokinetics.
Avery LB, Wade J, Wang M, Tam A, King A, Piche-Nicholas N, Kavosi MS, Penn S, Cirelli D, Kurz JC, Zhang M, Cunningham O, Jones R, Fennell BJ, McDonnell B, Sakorafas P, Apgar J, Finlay WJ, Lin L, Bloom L, O'Hara DM.
Avery LB, et al.
MAbs. 2018 Feb/Mar;10(2):244-255. doi: 10.1080/19420862.2017.1417718. Epub 2018 Jan 29.
MAbs. 2018.
PMID: 29271699
Free PMC article.
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