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RGD density along with substrate stiffness regulate hPSC hepatocyte functionality through YAP signalling.
Blackford SJI, Yu TTL, Norman MDA, Syanda AM, Manolakakis M, Lachowski D, Yan Z, Guo Y, Garitta E, Riccio F, Jowett GM, Ng SS, Vernia S, Del Río Hernández AE, Gentleman E, Rashid ST. Blackford SJI, et al. Among authors: gentleman e. Biomaterials. 2023 Feb;293:121982. doi: 10.1016/j.biomaterials.2022.121982. Epub 2022 Dec 22. Biomaterials. 2023. PMID: 36640555 Free article.
An engineered, quantifiable in vitro model for analysing the effect of proteostasis-targeting drugs on tissue physical properties.
Loaiza S, Ferreira SA, Chinn TM, Kirby A, Tsolaki E, Dondi C, Parzych K, Strange AP, Bozec L, Bertazzo S, Hedegaard MAB, Gentleman E, Auner HW. Loaiza S, et al. Among authors: gentleman e. Biomaterials. 2018 Nov;183:102-113. doi: 10.1016/j.biomaterials.2018.08.041. Epub 2018 Aug 21. Biomaterials. 2018. PMID: 30153561 Free PMC article.
Bi-directional cell-pericellular matrix interactions direct stem cell fate.
Ferreira SA, Motwani MS, Faull PA, Seymour AJ, Yu TTL, Enayati M, Taheem DK, Salzlechner C, Haghighi T, Kania EM, Oommen OP, Ahmed T, Loaiza S, Parzych K, Dazzi F, Varghese OP, Festy F, Grigoriadis AE, Auner HW, Snijders AP, Bozec L, Gentleman E. Ferreira SA, et al. Among authors: gentleman e. Nat Commun. 2018 Oct 3;9(1):4049. doi: 10.1038/s41467-018-06183-4. Nat Commun. 2018. PMID: 30282987 Free PMC article.
ILC1 drive intestinal epithelial and matrix remodelling.
Jowett GM, Norman MDA, Yu TTL, Rosell Arévalo P, Hoogland D, Lust ST, Read E, Hamrud E, Walters NJ, Niazi U, Chung MWH, Marciano D, Omer OS, Zabinski T, Danovi D, Lord GM, Hilborn J, Evans ND, Dreiss CA, Bozec L, Oommen OP, Lorenz CD, da Silva RMP, Neves JF, Gentleman E. Jowett GM, et al. Among authors: gentleman e. Nat Mater. 2021 Feb;20(2):250-259. doi: 10.1038/s41563-020-0783-8. Epub 2020 Sep 7. Nat Mater. 2021. PMID: 32895507 Free PMC article.
69 results