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Phase Ib open-label, multicenter study of pixatimod, an activator of TLR9, in combination with nivolumab in subjects with microsatellite-stable metastatic colorectal cancer, metastatic pancreatic ductal adenocarcinoma and other solid tumors.
J Immunother Cancer. 2023 Jan;11(1):e006136. doi: 10.1136/jitc-2022-006136.
J Immunother Cancer. 2023.
PMID: 36634920
Free PMC article.
Clinical Trial.
A Phase I study of the novel immunomodulatory agent PG545 (pixatimod) in subjects with advanced solid tumours.
Dredge K, Brennan TV, Hammond E, Lickliter JD, Lin L, Bampton D, Handley P, Lankesheer F, Morrish G, Yang Y, Brown MP, Millward M.
Dredge K, et al. Among authors: bampton d.
Br J Cancer. 2018 Apr;118(8):1035-1041. doi: 10.1038/s41416-018-0006-0. Epub 2018 Mar 13.
Br J Cancer. 2018.
PMID: 29531325
Free PMC article.
Clinical Trial.
Item in Clipboard
Immunomodulatory activities of pixatimod: emerging nonclinical and clinical data, and its potential utility in combination with PD-1 inhibitors.
Hammond E, Haynes NM, Cullinane C, Brennan TV, Bampton D, Handley P, Karoli T, Lanksheer F, Lin L, Yang Y, Dredge K.
Hammond E, et al. Among authors: bampton d.
J Immunother Cancer. 2018 Jun 14;6(1):54. doi: 10.1186/s40425-018-0363-5.
J Immunother Cancer. 2018.
PMID: 29898788
Free PMC article.
Item in Clipboard
PG545 enhances anti-cancer activity of chemotherapy in ovarian models and increases surrogate biomarkers such as VEGF in preclinical and clinical plasma samples.
Winterhoff B, Freyer L, Hammond E, Giri S, Mondal S, Roy D, Teoman A, Mullany SA, Hoffmann R, von Bismarck A, Chien J, Block MS, Millward M, Bampton D, Dredge K, Shridhar V.
Winterhoff B, et al. Among authors: bampton d.
Eur J Cancer. 2015 May;51(7):879-892. doi: 10.1016/j.ejca.2015.02.007. Epub 2015 Mar 5.
Eur J Cancer. 2015.
PMID: 25754234
Free PMC article.
Clinical Trial.
Item in Clipboard
Intentional injury reported by young people in the Federated States of Micronesia, Kingdom of Tonga and Vanuatu.
Smith BJ, Phongsavan P, Bampton D, Peacocke G, Gilmete M, Havea D, Chey T, Bauman AE.
Smith BJ, et al. Among authors: bampton d.
BMC Public Health. 2008 Apr 30;8:145. doi: 10.1186/1471-2458-8-145.
BMC Public Health. 2008.
PMID: 18447911
Free PMC article.
Item in Clipboard
Age-specific interval breast cancers in New South Wales and meta-analysis of studies of women aged 40-49 years.
Taylor R, Page A, Bampton D, Estoesta J, Rickard M.
Taylor R, et al. Among authors: bampton d.
J Med Screen. 2004;11(4):199-206. doi: 10.1258/0969141042467403.
J Med Screen. 2004.
PMID: 15563775
Item in Clipboard
Contemporary patterns of Pacific Island mortality.
Taylor R, Bampton D, Lopez AD.
Taylor R, et al. Among authors: bampton d.
Int J Epidemiol. 2005 Feb;34(1):207-14. doi: 10.1093/ije/dyh337. Epub 2004 Oct 1.
Int J Epidemiol. 2005.
PMID: 15465904
Review.
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