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TRPA1 as a potential factor and drug target in scleroderma: dermal fibrosis and alternative macrophage activation are attenuated in TRPA1-deficient mice in bleomycin-induced experimental model of scleroderma.
Arthritis Res Ther. 2023 Jan 25;25(1):12. doi: 10.1186/s13075-023-02994-z.
Arthritis Res Ther. 2023.
PMID: 36698198
Free PMC article.
TRPA1 Mediates Contact Hypersensitivity Induced by 2,4-Dinitrochlorobenzene.
Mäki-Opas I, Hämäläinen M, Moilanen LJ, Sood H, Leppänen T, Kummola L, Junttila IS, Lehtimäki L, Moilanen E.
Mäki-Opas I, et al.
J Invest Dermatol. 2023 Jun;143(6):1104-1108.e4. doi: 10.1016/j.jid.2022.12.014. Epub 2023 Jan 10.
J Invest Dermatol. 2023.
PMID: 36634816
Free article.
No abstract available.
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Pyrazine-Fused Triterpenoids Block the TRPA1 Ion Channel in Vitro and Inhibit TRPA1-Mediated Acute Inflammation in Vivo.
Mäki-Opas I, Hämäläinen M, Moilanen LJ, Haavikko R, Ahonen TJ, Alakurtti S, Moreira VM, Muraki K, Yli-Kauhaluoma J, Moilanen E.
Mäki-Opas I, et al.
ACS Chem Neurosci. 2019 Jun 19;10(6):2848-2857. doi: 10.1021/acschemneuro.9b00083. Epub 2019 Apr 29.
ACS Chem Neurosci. 2019.
PMID: 31034197
Free article.
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Natural Stilbenoids Have Anti-Inflammatory Properties in Vivo and Down-Regulate the Production of Inflammatory Mediators NO, IL6, and MCP1 Possibly in a PI3K/Akt-Dependent Manner.
Eräsalo H, Hämäläinen M, Leppänen T, Mäki-Opas I, Laavola M, Haavikko R, Yli-Kauhaluoma J, Moilanen E.
Eräsalo H, et al. Among authors: maki opas i.
J Nat Prod. 2018 May 25;81(5):1131-1142. doi: 10.1021/acs.jnatprod.7b00384. Epub 2018 May 4.
J Nat Prod. 2018.
PMID: 29726680
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