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A combined physiologically-based pharmacokinetic and quantitative systems pharmacology model for modeling amyloid aggregation in Alzheimer's disease.
Geerts H, Walker M, Rose R, Bergeler S, van der Graaf PH, Schuck E, Koyama A, Yasuda S, Hussein Z, Reyderman L, Swanson C, Cabal A. Geerts H, et al. Among authors: yasuda s. CPT Pharmacometrics Syst Pharmacol. 2023 Apr;12(4):444-461. doi: 10.1002/psp4.12912. Epub 2023 Jan 20. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 36632701 Free PMC article.
Population pharmacokinetic-pharmacodynamic analyses of amyloid positron emission tomography and plasma biomarkers for lecanemab in subjects with early Alzheimer's disease.
Hayato S, Takenaka O, Sreerama Reddy SH, Landry I, Reyderman L, Koyama A, Swanson C, Yasuda S, Hussein Z. Hayato S, et al. Among authors: yasuda s. CPT Pharmacometrics Syst Pharmacol. 2022 Dec;11(12):1578-1591. doi: 10.1002/psp4.12862. Epub 2022 Sep 27. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 36165093 Free PMC article.
Population pharmacokinetic-pharmacodynamic modeling of serum biomarkers as predictors of tumor dynamics following lenvatinib treatment in patients with radioiodine-refractory differentiated thyroid cancer (RR-DTC).
Majid O, Hayato S, Sreerama Reddy SH, Lalovic B, Hihara T, Hoshi T, Funahashi Y, Aluri J, Takenaka O, Yasuda S, Hussein Z. Majid O, et al. Among authors: yasuda s. CPT Pharmacometrics Syst Pharmacol. 2024 Mar 26. doi: 10.1002/psp4.13130. Online ahead of print. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 38528813 Free article.
Concentration-Response Modeling of ECG Data From Early-Phase Clinical Studies as an Alternative Clinical and Regulatory Approach to Assessing QT Risk - Experience From the Development Program of Lemborexant.
Murphy PJ, Yasuda S, Nakai K, Yoshinaga T, Hall N, Zhou M, Aluri J, Rege B, Moline M, Ferry J, Darpo B. Murphy PJ, et al. Among authors: yasuda s. J Clin Pharmacol. 2017 Jan;57(1):96-104. doi: 10.1002/jcph.785. Epub 2016 Aug 4. J Clin Pharmacol. 2017. PMID: 27338807 Clinical Trial.
Regulatory Effects of Antioxidants on Indoxyl Sulfate-Enhanced Intracellular Oxidation and Impaired Phagocytic Activity in Differentiated U937 Human Macrophage Cells.
Iwamoto W, Ikeda T, Nishikawa H, Hirano M, Kinoshita H, Ono M, Kurogi K, Sakakibara Y, Suiko M, Yasuda S. Iwamoto W, et al. Among authors: yasuda s. Biosci Biotechnol Biochem. 2024 Jun 7:zbae077. doi: 10.1093/bbb/zbae077. Online ahead of print. Biosci Biotechnol Biochem. 2024. PMID: 38849302
Mitral regurgitation is associated with similar loss of von Willebrand factor large multimers but lower frequency of anemia compared with aortic stenosis.
Takiguchi H, Miura M, Shirai SI, Soga Y, Hanyu M, Sakaguchi G, Soga Y, Arai Y, Watanabe S, Kimura T, Takahama H, Yasuda S, Nakayoshi T, Fukumoto Y, Yaoita N, Shimokawa H, Sakatsume K, Saiki Y, Kaikita K, Tsujita K, Tamura T, Doman T, Yamashita M, Suzuki M, Eura Y, Kokame K, Hayakawa M, Matsumoto M, Okubo N, Sugawara S, Fujimaki SI, Kawate Y, Ando K, Horiuchi H. Takiguchi H, et al. Among authors: yasuda s. Res Pract Thromb Haemost. 2024 May 3;8(4):102431. doi: 10.1016/j.rpth.2024.102431. eCollection 2024 May. Res Pract Thromb Haemost. 2024. PMID: 38840664 Free PMC article.
2,517 results