Kline GM - Search Results

1

Capturing the conversion of the pathogenic alpha-1-antitrypsin fold by ATF6 enhanced proteostasis.

Sun S, Wang C, Zhao P, Kline GM, Grandjean JMD, Jiang X, Labaudiniere R, Wiseman RL, Kelly JW, Balch WE. Sun S, et al. Among authors: kline gm. Cell Chem Biol. 2023 Jan 19;30(1):22-42.e5. doi: 10.1016/j.chembiol.2022.12.004. Epub 2023 Jan 10. Cell Chem Biol. 2023. PMID: 36630963 Free PMC article.

2

Metabolically Activated Proteostasis Regulators Protect against Glutamate Toxicity by Activating NRF2.

Rosarda JD, Baron KR, Nutsch K, Kline GM, Stanton C, Kelly JW, Bollong MJ, Wiseman RL. Rosarda JD, et al. Among authors: kline gm. ACS Chem Biol. 2021 Dec 17;16(12):2852-2863. doi: 10.1021/acschembio.1c00810. Epub 2021 Nov 19. ACS Chem Biol. 2021. PMID: 34797633 Free PMC article.

3

Inverse Drug Discovery identifies weak electrophiles affording protein conjugates.

Kline GM, Nugroho K, Kelly JW. Kline GM, et al. Curr Opin Chem Biol. 2022 Apr;67:102113. doi: 10.1016/j.cbpa.2021.102113. Epub 2022 Jan 20. Curr Opin Chem Biol. 2022. PMID: 35065430 Free PMC article. Review.

4

Characterising diflunisal as a transthyretin kinetic stabilizer at relevant concentrations in human plasma using subunit exchange.

Tsai FJ, Nelson LT, Kline GM, Jäger M, Berk JL, Sekijima Y, Powers ET, Kelly JW. Tsai FJ, et al. Among authors: kline gm. Amyloid. 2023 Jun;30(2):220-224. doi: 10.1080/13506129.2022.2148094. Epub 2022 Nov 29. Amyloid. 2023. PMID: 36444793

5

Divergent Proteome Reactivity Influences Arm-Selective Activation of the Unfolded Protein Response by Pharmacological Endoplasmic Reticulum Proteostasis Regulators.

Kline GM, Paxman RJ, Lin CY, Madrazo N, Yoon L, Grandjean JMD, Lee K, Nugroho K, Powers ET, Wiseman RL, Kelly JW. Kline GM, et al. ACS Chem Biol. 2023 Aug 18;18(8):1719-1729. doi: 10.1021/acschembio.3c00042. Epub 2023 Jul 31. ACS Chem Biol. 2023. PMID: 37523656 Free PMC article.

6

The conformational landscape of human transthyretin revealed by cryo-EM.

Basanta B, Nugroho K, Yan NL, Kline GM, Powers ET, Tsai FJ, Wu M, Hansel-Harris A, Chen JS, Forli S, Kelly JW, Lander GC. Basanta B, et al. Among authors: kline gm. bioRxiv [Preprint]. 2024 Jan 23:2024.01.23.576879. doi: 10.1101/2024.01.23.576879. bioRxiv. 2024. PMID: 38328110 Free PMC article. Preprint.

7

Divergent Proteome Reactivity Influences Arm-Selective Activation of Pharmacological Endoplasmic Reticulum Proteostasis Regulators.

Kline GM, Paxman RJ, Lin CY, Madrazo N, Grandjean JM, Lee K, Nugroho K, Powers ET, Wiseman RL, Kelly JW. Kline GM, et al. bioRxiv [Preprint]. 2023 Jan 17:2023.01.16.524237. doi: 10.1101/2023.01.16.524237. bioRxiv. 2023. PMID: 36712115 Free PMC article. Updated. Preprint.

8

Development and validation of a one-mile treadmill walk test to predict peak oxygen uptake in healthy adults ages 40 to 79 years.

Pober DM, Freedson PS, Kline GM, McInnis KJ, Rippe JM. Pober DM, et al. Among authors: kline gm. Can J Appl Physiol. 2002 Dec;27(6):575-89. doi: 10.1139/h02-033. Can J Appl Physiol. 2002. PMID: 12500996 Clinical Trial.

9

Routine myocardial revascularization with the radial artery: a multicenter experience.

Chen AM, Brodman RF, Frame R, Graver LM, Tranbaugh RF, Banks T, Hoffman D, Palazzo RS, Kline GM, Stelzer P, Harris L, Sisto D, Frymus M, Frater RW, Furlong P, Wasserman F, Cohen B. Chen AM, et al. Among authors: kline gm. J Card Surg. 1998 Sep-Oct;13(5):318-27. doi: 10.1111/j.1540-8191.1998.tb01092.x. J Card Surg. 1998. PMID: 10440646 Clinical Trial.

10

Relation of gender to physician use of test results and to the prognostic value of stress technetium 99m sestamibi myocardial single-photon emission computed tomography scintigraphy.

Travin MI, Duca MD, Kline GM, Herman SD, Demus DD, Heller GV. Travin MI, et al. Among authors: kline gm. Am Heart J. 1997 Jul;134(1):73-82. doi: 10.1016/s0002-8703(97)70109-1. Am Heart J. 1997. PMID: 9266786

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