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Improved cytosine base editors generated from TadA variants.
Lam DK, Feliciano PR, Arif A, Bohnuud T, Fernandez TP, Gehrke JM, Grayson P, Lee KD, Ortega MA, Sawyer C, Schwaegerle ND, Peraro L, Young L, Lee SJ, Ciaramella G, Gaudelli NM. Lam DK, et al. Nat Biotechnol. 2023 May;41(5):686-697. doi: 10.1038/s41587-022-01611-9. Epub 2023 Jan 9. Nat Biotechnol. 2023. PMID: 36624149 Free PMC article.
Directed evolution of adenine base editors with increased activity and therapeutic application.
Gaudelli NM, Lam DK, Rees HA, Solá-Esteves NM, Barrera LA, Born DA, Edwards A, Gehrke JM, Lee SJ, Liquori AJ, Murray R, Packer MS, Rinaldi C, Slaymaker IM, Yen J, Young LE, Ciaramella G. Gaudelli NM, et al. Among authors: lam dk. Nat Biotechnol. 2020 Jul;38(7):892-900. doi: 10.1038/s41587-020-0491-6. Epub 2020 Apr 13. Nat Biotechnol. 2020. PMID: 32284586
Spatial subsetting enables integrative modeling of oral squamous cell carcinoma multiplex imaging data.
Einhaus J, Gaudilliere DK, Hedou J, Feyaerts D, Ozawa MG, Sato M, Ganio EA, Tsai AS, Stelzer IA, Bruckman KC, Amar JN, Sabayev M, Bonham TA, Gillard J, Diop M, Cambriel A, Mihalic ZN, Valdez T, Liu SY, Feirrera L, Lam DK, Sunwoo JB, Schürch CM, Gaudilliere B, Han X. Einhaus J, et al. Among authors: lam dk. iScience. 2023 Nov 20;26(12):108486. doi: 10.1016/j.isci.2023.108486. eCollection 2023 Dec 15. iScience. 2023. PMID: 38125025 Free PMC article.
90 results