DEPP/DEPP1/C10ORF10 regulates hepatic glucose and fat metabolism partly via ROS-induced FGF21.
Li W, Ji M, Lin Y, Miao Y, Chen S, Li H.
Li W, et al. Among authors: li h.
FASEB J. 2018 Oct;32(10):5459-5469. doi: 10.1096/fj.201800357R. Epub 2018 Apr 27.
FASEB J. 2018.
PMID: 29702025
Hepatic overexpression of DEPP in mice promotes fatty acid oxidation and ketogenesis and suppresses lipogenesis and gluconeogenesis, which is partly mediated by FGF21 induced by elevated cellular ROS levels.-Li, W., Ji, M., Lin, Y., Miao, Y., Chen, S., Li, H. …
Hepatic overexpression of DEPP in mice promotes fatty acid oxidation and ketogenesis and suppresses lipogenesis and gluconeogenesis, which i …