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The Inhibitory Properties of a Novel, Selective LMTK3 Kinase Inhibitor.
Agnarelli A, Lauer Betrán A, Papakyriakou A, Vella V, Samuels M, Papanastasopoulos P, Giamas C, Mancini EJ, Stebbing J, Spencer J, Cilibrasi C, Ditsiou A, Giamas G. Agnarelli A, et al. Among authors: spencer j. Int J Mol Sci. 2023 Jan 3;24(1):865. doi: 10.3390/ijms24010865. Int J Mol Sci. 2023. PMID: 36614307 Free PMC article.
The structure-function relationship of oncogenic LMTK3.
Ditsiou A, Cilibrasi C, Simigdala N, Papakyriakou A, Milton-Harris L, Vella V, Nettleship JE, Lo JH, Soni S, Smbatyan G, Ntavelou P, Gagliano T, Iachini MC, Khurshid S, Simon T, Zhou L, Hassell-Hart S, Carter P, Pearl LH, Owen RL, Owens RJ, Roe SM, Chayen NE, Lenz HJ, Spencer J, Prodromou C, Klinakis A, Stebbing J, Giamas G. Ditsiou A, et al. Among authors: spencer j. Sci Adv. 2020 Nov 13;6(46):eabc3099. doi: 10.1126/sciadv.abc3099. Print 2020 Nov. Sci Adv. 2020. PMID: 33188023 Free PMC article.
A cyclodextrin-capped histone deacetylase inhibitor.
Amin J, Puglisi A, Clarke J, Milton J, Wang M, Paranal RM, Bradner JE, Spencer J. Amin J, et al. Among authors: spencer j. Bioorg Med Chem Lett. 2013 Jun 1;23(11):3346-8. doi: 10.1016/j.bmcl.2013.03.084. Epub 2013 Apr 2. Bioorg Med Chem Lett. 2013. PMID: 23591111
Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety.
Sansook S, Ocasio CA, Day IJ, Tizzard GJ, Coles SJ, Fedorov O, Bennett JM, Elkins JM, Spencer J. Sansook S, et al. Among authors: spencer j. Org Biomol Chem. 2017 Oct 18;15(40):8655-8660. doi: 10.1039/c7ob02289a. Org Biomol Chem. 2017. PMID: 28984325 Free PMC article.
3,056 results