Özvegy-Laczka C - Search Results

1

Metal Complexes of a 5-Nitro-8-Hydroxyquinoline-Proline Hybrid with Enhanced Water Solubility Targeting Multidrug Resistant Cancer Cells.

Pivarcsik T, Pósa V, Kovács H, May NV, Spengler G, Pósa SP, Tóth S, Nezafat Yazdi Z, Özvegy-Laczka C, Ugrai I, Szatmári I, Szakács G, Enyedy ÉA. Pivarcsik T, et al. Among authors: ozvegy laczka c. Int J Mol Sci. 2022 Dec 29;24(1):593. doi: 10.3390/ijms24010593. Int J Mol Sci. 2022. PMID: 36614037 Free PMC article.

2

Single nucleotide polymorphisms modify the transporter activity of ABCG2.

Morisaki K, Robey RW, Ozvegy-Laczka C, Honjo Y, Polgar O, Steadman K, Sarkadi B, Bates SE. Morisaki K, et al. Cancer Chemother Pharmacol. 2005 Aug;56(2):161-72. doi: 10.1007/s00280-004-0931-x. Epub 2005 Apr 19. Cancer Chemother Pharmacol. 2005. PMID: 15838659

3

Inhibitory Effects of Quercetin and Its Main Methyl, Sulfate, and Glucuronic Acid Conjugates on Cytochrome P450 Enzymes, and on OATP, BCRP and MRP2 Transporters.

Mohos V, Fliszár-Nyúl E, Ungvári O, Kuffa K, Needs PW, Kroon PA, Telbisz Á, Özvegy-Laczka C, Poór M. Mohos V, et al. Nutrients. 2020 Jul 31;12(8):2306. doi: 10.3390/nu12082306. Nutrients. 2020. PMID: 32751996 Free PMC article.

4

The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox).

Szakács G, Váradi A, Ozvegy-Laczka C, Sarkadi B. Szakács G, et al. Drug Discov Today. 2008 May;13(9-10):379-93. doi: 10.1016/j.drudis.2007.12.010. Epub 2008 Feb 20. Drug Discov Today. 2008. PMID: 18468555 Review.

5

Interaction of ABC multidrug transporters with anticancer protein kinase inhibitors: substrates and/or inhibitors?

Hegedus C, Ozvegy-Laczka C, Szakács G, Sarkadi B. Hegedus C, et al. Curr Cancer Drug Targets. 2009 May;9(3):252-72. doi: 10.2174/156800909788166565. Curr Cancer Drug Targets. 2009. PMID: 19442047 Review.

6

Interaction of nilotinib, dasatinib and bosutinib with ABCB1 and ABCG2: implications for altered anti-cancer effects and pharmacological properties.

Hegedus C, Ozvegy-Laczka C, Apáti A, Magócsi M, Német K, Orfi L, Kéri G, Katona M, Takáts Z, Váradi A, Szakács G, Sarkadi B. Hegedus C, et al. Br J Pharmacol. 2009 Oct;158(4):1153-64. doi: 10.1111/j.1476-5381.2009.00383.x. Epub 2009 Sep 28. Br J Pharmacol. 2009. PMID: 19785662 Free PMC article.

7

Tyrosine kinase inhibitors as modulators of ATP binding cassette multidrug transporters: substrates, chemosensitizers or inducers of acquired multidrug resistance?

Brózik A, Hegedüs C, Erdei Z, Hegedus T, Özvegy-Laczka C, Szakács G, Sarkadi B. Brózik A, et al. Expert Opin Drug Metab Toxicol. 2011 May;7(5):623-42. doi: 10.1517/17425255.2011.562892. Epub 2011 Mar 17. Expert Opin Drug Metab Toxicol. 2011. PMID: 21410427 Review.

8

Interaction of the EGFR inhibitors gefitinib, vandetanib, pelitinib and neratinib with the ABCG2 multidrug transporter: implications for the emergence and reversal of cancer drug resistance.

Hegedüs C, Truta-Feles K, Antalffy G, Várady G, Német K, Ozvegy-Laczka C, Kéri G, Orfi L, Szakács G, Settleman J, Váradi A, Sarkadi B. Hegedüs C, et al. Biochem Pharmacol. 2012 Aug 1;84(3):260-7. doi: 10.1016/j.bcp.2012.04.010. Epub 2012 Apr 21. Biochem Pharmacol. 2012. PMID: 22548830

9

ABCG2 is not able to catalyze glutathione efflux and does not contribute to GSH-dependent collateral sensitivity.

Gauthier C, Ozvegy-Laczka C, Szakacs G, Sarkadi B, Di Pietro A. Gauthier C, et al. Front Pharmacol. 2013 Nov 7;4:138. doi: 10.3389/fphar.2013.00138. eCollection 2013. Front Pharmacol. 2013. PMID: 24312054 Free PMC article.

10

Mutations of the central tyrosines of putative cholesterol recognition amino acid consensus (CRAC) sequences modify folding, activity, and sterol-sensing of the human ABCG2 multidrug transporter.

Gál Z, Hegedüs C, Szakács G, Váradi A, Sarkadi B, Özvegy-Laczka C. Gál Z, et al. Biochim Biophys Acta. 2015 Feb;1848(2):477-87. doi: 10.1016/j.bbamem.2014.11.006. Epub 2014 Nov 14. Biochim Biophys Acta. 2015. PMID: 25445676 Free article.

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