Jacquemyn M - Search Results

1

CRISPR-Cas9 recognition of enzymatically synthesized base-modified nucleic acids.

Yang H, Eremeeva E, Abramov M, Jacquemyn M, Groaz E, Daelemans D, Herdewijn P. Yang H, et al. Among authors: jacquemyn m. Nucleic Acids Res. 2023 Feb 28;51(4):1501-1511. doi: 10.1093/nar/gkac1147. Nucleic Acids Res. 2023. PMID: 36611237 Free PMC article.

2

Identifying drug-target selectivity of small-molecule CRM1/XPO1 inhibitors by CRISPR/Cas9 genome editing.

Neggers JE, Vercruysse T, Jacquemyn M, Vanstreels E, Baloglu E, Shacham S, Crochiere M, Landesman Y, Daelemans D. Neggers JE, et al. Among authors: jacquemyn m. Chem Biol. 2015 Jan 22;22(1):107-16. doi: 10.1016/j.chembiol.2014.11.015. Epub 2015 Jan 8. Chem Biol. 2015. PMID: 25579209

3

Human Exportin-1 is a Target for Combined Therapy of HIV and AIDS Related Lymphoma.

Boons E, Vanstreels E, Jacquemyn M, Nogueira TC, Neggers JE, Vercruysse T, van den Oord J, Tamir S, Shacham S, Landesman Y, Snoeck R, Pannecouque C, Andrei G, Daelemans D. Boons E, et al. Among authors: jacquemyn m. EBioMedicine. 2015 Aug 1;2(9):1102-13. doi: 10.1016/j.ebiom.2015.07.041. eCollection 2015 Sep. EBioMedicine. 2015. PMID: 26501108 Free PMC article.

4

The Second-Generation Exportin-1 Inhibitor KPT-8602 Demonstrates Potent Activity against Acute Lymphoblastic Leukemia.

Vercruysse T, De Bie J, Neggers JE, Jacquemyn M, Vanstreels E, Schmid-Burgk JL, Hornung V, Baloglu E, Landesman Y, Senapedis W, Shacham S, Dagklis A, Cools J, Daelemans D. Vercruysse T, et al. Among authors: jacquemyn m. Clin Cancer Res. 2017 May 15;23(10):2528-2541. doi: 10.1158/1078-0432.CCR-16-1580. Epub 2016 Oct 25. Clin Cancer Res. 2017. PMID: 27780859

5

Target identification of small molecules using large-scale CRISPR-Cas mutagenesis scanning of essential genes.

Neggers JE, Kwanten B, Dierckx T, Noguchi H, Voet A, Bral L, Minner K, Massant B, Kint N, Delforge M, Vercruysse T, Baloglu E, Senapedis W, Jacquemyn M, Daelemans D. Neggers JE, et al. Among authors: jacquemyn m. Nat Commun. 2018 Feb 5;9(1):502. doi: 10.1038/s41467-017-02349-8. Nat Commun. 2018. PMID: 29402884 Free PMC article.

6

Targeting the XPO1-dependent nuclear export of E2F7 reverses anthracycline resistance in head and neck squamous cell carcinomas.

Saenz-Ponce N, Pillay R, de Long LM, Kashyap T, Argueta C, Landesman Y, Hazar-Rethinam M, Boros S, Panizza B, Jacquemyn M, Daelemans D, Gannon OM, Saunders NA. Saenz-Ponce N, et al. Among authors: jacquemyn m. Sci Transl Med. 2018 Jun 27;10(447):eaar7223. doi: 10.1126/scitranslmed.aar7223. Sci Transl Med. 2018. PMID: 29950445

7

STK38 kinase acts as XPO1 gatekeeper regulating the nuclear export of autophagy proteins and other cargoes.

Martin AP, Jacquemyn M, Lipecka J, Chhuon C, Aushev VN, Meunier B, Singh MK, Carpi N, Piel M, Codogno P, Hergovich A, Parrini MC, Zalcman G, Guerrera IC, Daelemans D, Camonis JH. Martin AP, et al. Among authors: jacquemyn m. EMBO Rep. 2019 Nov 5;20(11):e48150. doi: 10.15252/embr.201948150. Epub 2019 Sep 23. EMBO Rep. 2019. PMID: 31544310 Free PMC article.

8

enAsCas12a Enables CRISPR-Directed Evolution to Screen for Functional Drug Resistance Mutations in Sequences Inaccessible to SpCas9.

Neggers JE, Jacquemyn M, Dierckx T, Kleinstiver BP, Thibaut HJ, Daelemans D. Neggers JE, et al. Among authors: jacquemyn m. Mol Ther. 2021 Jan 6;29(1):208-224. doi: 10.1016/j.ymthe.2020.09.025. Epub 2020 Sep 20. Mol Ther. 2021. PMID: 33002419 Free PMC article.

9

Loss of tRNA-modifying enzyme Elp3 activates a p53-dependent antitumor checkpoint in hematopoiesis.

Rosu A, El Hachem N, Rapino F, Rouault-Pierre K, Jorssen J, Somja J, Ramery E, Thiry M, Nguyen L, Jacquemyn M, Daelemans D, Adams CM, Bonnet D, Chariot A, Close P, Bureau F, Desmet CJ. Rosu A, et al. Among authors: jacquemyn m. J Exp Med. 2021 Mar 1;218(3):e20200662. doi: 10.1084/jem.20200662. J Exp Med. 2021. PMID: 33507234 Free PMC article.

10

XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53-mediated caspase-dependent apoptosis.

Boons E, Nogueira TC, Dierckx T, Menezes SM, Jacquemyn M, Tamir S, Landesman Y, Farré L, Bittencourt A, Kataoka K, Ogawa S, Snoeck R, Andrei G, Van Weyenbergh J, Daelemans D. Boons E, et al. Among authors: jacquemyn m. Blood Cancer J. 2021 Feb 1;11(2):27. doi: 10.1038/s41408-021-00409-3. Blood Cancer J. 2021. PMID: 33563902 Free PMC article. No abstract available.

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