Chen YH - Search Results

1

Cochlear transduction via cerebrospinal fluid delivery of AAV in non-human primates.

Ranum PT, Tecedor L, Keiser MS, Chen YH, Leib DE, Liu X, Davidson BL. Ranum PT, et al. Among authors: chen yh. Mol Ther. 2023 Mar 1;31(3):609-612. doi: 10.1016/j.ymthe.2022.12.018. Epub 2023 Jan 6. Mol Ther. 2023. PMID: 36610400 Free PMC article. No abstract available.

2

Adeno-associated virus type 5 reduces learning deficits and restores glutamate receptor subunit levels in MPS VII mice CNS.

Liu G, Chen YH, He X, Martins I, Heth JA, Chiorini JA, Davidson BL. Liu G, et al. Among authors: chen yh. Mol Ther. 2007 Feb;15(2):242-7. doi: 10.1038/sj.mt.6300016. Mol Ther. 2007. PMID: 17235300 Free article.

3

Molecular signatures of disease brain endothelia provide new sites for CNS-directed enzyme therapy.

Chen YH, Chang M, Davidson BL. Chen YH, et al. Nat Med. 2009 Oct;15(10):1215-8. doi: 10.1038/nm.2025. Epub 2009 Sep 13. Nat Med. 2009. PMID: 19749771 Free PMC article.

4

Sialic acid deposition impairs the utility of AAV9, but not peptide-modified AAVs for brain gene therapy in a mouse model of lysosomal storage disease.

Chen YH, Claflin K, Geoghegan JC, Davidson BL. Chen YH, et al. Mol Ther. 2012 Jul;20(7):1393-9. doi: 10.1038/mt.2012.100. Epub 2012 May 15. Mol Ther. 2012. PMID: 22588273 Free PMC article.

5

In vivo SELEX for Identification of Brain-penetrating Aptamers.

Cheng C, Chen YH, Lennox KA, Behlke MA, Davidson BL. Cheng C, et al. Among authors: chen yh. Mol Ther Nucleic Acids. 2013 Jan 8;2(1):e67. doi: 10.1038/mtna.2012.59. Mol Ther Nucleic Acids. 2013. PMID: 23299833 Free PMC article.

6

A novel gene delivery method transduces porcine pancreatic duct epithelial cells.

Griffin MA, Restrepo MS, Abu-El-Haija M, Wallen T, Buchanan E, Rokhlina T, Chen YH, McCray PB Jr, Davidson BL, Divekar A, Uc A. Griffin MA, et al. Among authors: chen yh. Gene Ther. 2014 Feb;21(2):123-30. doi: 10.1038/gt.2013.62. Epub 2013 Nov 21. Gene Ther. 2014. PMID: 24257348 Free PMC article.

7

Reinstating aberrant mTORC1 activity in Huntington's disease mice improves disease phenotypes.

Lee JH, Tecedor L, Chen YH, Monteys AM, Sowada MJ, Thompson LM, Davidson BL. Lee JH, et al. Among authors: chen yh. Neuron. 2015 Jan 21;85(2):303-15. doi: 10.1016/j.neuron.2014.12.019. Epub 2014 Dec 31. Neuron. 2015. PMID: 25556834 Free PMC article.

8

AAV gene transfer delays disease onset in a TPP1-deficient canine model of the late infantile form of Batten disease.

Katz ML, Tecedor L, Chen Y, Williamson BG, Lysenko E, Wininger FA, Young WM, Johnson GC, Whiting RE, Coates JR, Davidson BL. Katz ML, et al. Sci Transl Med. 2015 Nov 11;7(313):313ra180. doi: 10.1126/scitranslmed.aac6191. Sci Transl Med. 2015. PMID: 26560358 Free PMC article.

9

Overcoming Limitations Inherent in Sulfamidase to Improve Mucopolysaccharidosis IIIA Gene Therapy.

Chen Y, Zheng S, Tecedor L, Davidson BL. Chen Y, et al. Mol Ther. 2018 Apr 4;26(4):1118-1126. doi: 10.1016/j.ymthe.2018.01.010. Epub 2018 Jan 31. Mol Ther. 2018. PMID: 29503202 Free PMC article.

10

Cardiac mTORC1 Dysregulation Impacts Stress Adaptation and Survival in Huntington's Disease.

Child DD, Lee JH, Pascua CJ, Chen YH, Mas Monteys A, Davidson BL. Child DD, et al. Among authors: chen yh. Cell Rep. 2018 Apr 24;23(4):1020-1033. doi: 10.1016/j.celrep.2018.03.117. Cell Rep. 2018. PMID: 29694882 Free PMC article.

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