Eichenbaum GE - Search Results

1

Preclinical safety assessment of JNJ-10450232 (NTM-006), a structural analog of acetaminophen, that does not cause hepatotoxicity at supratherapeutic doses.

Zhou J, De Jonghe S, Codd EE, Weiner S, Gallacher D, Stahle P, Kelley MF, Kuffner EK, Flores CM, Eichenbaum GE. Zhou J, et al. Among authors: eichenbaum ge. Regul Toxicol Pharmacol. 2023 Jan 4:105334. doi: 10.1016/j.yrtph.2023.105334. Online ahead of print. Regul Toxicol Pharmacol. 2023. PMID: 36608923 Free article.

2

Assessment of the genotoxic and carcinogenic risks of p-nitrophenol when it is present as an impurity in a drug product.

Eichenbaum G, Johnson M, Kirkland D, O'Neill P, Stellar S, Bielawne J, DeWire R, Areia D, Bryant S, Weiner S, Desai-Krieger D, Guzzie-Peck P, Evans DC, Tonelli A. Eichenbaum G, et al. Regul Toxicol Pharmacol. 2009 Oct;55(1):33-42. doi: 10.1016/j.yrtph.2009.05.018. Epub 2009 Jun 14. Regul Toxicol Pharmacol. 2009. PMID: 19500632 Review.

3

Impact of gavage dosing procedure and gastric content on adverse respiratory effects and mortality in rat toxicity studies.

Eichenbaum G, Damsch S, Looszova A, Vandenberghe J, Van den Bulck K, Roels K, Megens A, Knight E, Hillsamer V, Feyen B, Kelley MF, Tonelli A, Lammens L. Eichenbaum G, et al. J Appl Toxicol. 2011 May;31(4):342-54. doi: 10.1002/jat.1592. Epub 2010 Nov 18. J Appl Toxicol. 2011. PMID: 21089156

4

Unexpected nasal changes in rats related to reflux after gavage dosing.

Damsch S, Eichenbaum G, Looszova A, Lammens L, Feyen B, Van den Bulck K, Knight E, Kelley M, Tonelli A. Damsch S, et al. Toxicol Pathol. 2011 Feb;39(2):337-47. doi: 10.1177/0192623310388430. Epub 2010 Dec 14. Toxicol Pathol. 2011. PMID: 21422260

5

Gavage-related reflux in rats: identification, pathogenesis, and toxicological implications (review).

Damsch S, Eichenbaum G, Tonelli A, Lammens L, Van den Bulck K, Feyen B, Vandenberghe J, Megens A, Knight E, Kelley M. Damsch S, et al. Toxicol Pathol. 2011 Feb;39(2):348-60. doi: 10.1177/0192623310388431. Epub 2010 Dec 14. Toxicol Pathol. 2011. PMID: 21422261 Review.

6

Role of mixed ion channel effects in the cardiovascular safety assessment of the novel anti-MRSA fluoroquinolone JNJ-Q2.

Eichenbaum G, Pugsley MK, Gallacher DJ, Towart R, McIntyre G, Shukla U, Davenport JM, Lu HR, Rohrbacher J, Hillsamer V. Eichenbaum G, et al. Br J Pharmacol. 2012 Jul;166(5):1694-707. doi: 10.1111/j.1476-5381.2012.01874.x. Br J Pharmacol. 2012. PMID: 22289150 Free PMC article. Clinical Trial.

7

Methods to evaluate and improve the injection site tolerability of intravenous formulations prior to first-in-human testing.

Eichenbaum G, Zhou J, De Smedt A, De Jonghe S, Looszova A, Arien T, Van Goethem F, Vervoort I, Shukla U, Lammens L. Eichenbaum G, et al. J Pharmacol Toxicol Methods. 2013 Nov-Dec;68(3):394-406. doi: 10.1016/j.vascn.2013.08.002. Epub 2013 Aug 8. J Pharmacol Toxicol Methods. 2013. PMID: 23933112

8

Implications of retinal effects observed in chronic toxicity studies on the clinical development of a CNS-active drug candidate.

Eichenbaum G, Zhou J, Kelley MF, Roosen W, Costa-Giomi P, Louden C, Di Prospero NA, Pandina G, Singh JB, Ford L, Moyer JA, Nork TM, Ver Hoeve JN, Aguirre GD. Eichenbaum G, et al. Regul Toxicol Pharmacol. 2014 Jul;69(2):187-200. doi: 10.1016/j.yrtph.2014.03.005. Epub 2014 Mar 26. Regul Toxicol Pharmacol. 2014. PMID: 24680767

9

Timing is everything for sperm assessment in fertility studies.

Mariën D, Bailey GP, Eichenbaum G, De Jonghe S. Mariën D, et al. Reprod Toxicol. 2016 Sep;64:141-50. doi: 10.1016/j.reprotox.2016.05.001. Epub 2016 May 12. Reprod Toxicol. 2016. PMID: 27181369

10

A kinetic-based safety assessment of consumer exposure to salicylic acid from cosmetic products demonstrates no evidence of a health risk from developmental toxicity.

Labib R, Bury D, Boisleve F, Eichenbaum G, Girard S, Naciff J, Leal M, Wong J. Labib R, et al. Regul Toxicol Pharmacol. 2018 Apr;94:245-251. doi: 10.1016/j.yrtph.2018.01.026. Epub 2018 Feb 21. Regul Toxicol Pharmacol. 2018. PMID: 29410076 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

38 results

Search Page