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Page 1
IL-10-producing Th1 cells possess a distinct molecular signature in malaria.
Edwards CL, Ng SS, de Labastida Rivera F, Corvino D, Engel JA, Montes de Oca M, Bukali L, Frame TC, Bunn PT, Chauhan SB, Singh SS, Wang Y, Na J, Amante FH, Loughland JR, Soon MS, Waddell N, Mukhopadhay P, Koufariotis LT, Johnston RL, Lee JS, Kuns R, Zhang P, Boyle MJ, Hill GR, McCarthy JS, Kumar R, Engwerda CR. Edwards CL, et al. Among authors: loughland jr. J Clin Invest. 2023 Jan 3;133(1):e153733. doi: 10.1172/JCI153733. J Clin Invest. 2023. PMID: 36594463 Free PMC article.
Profoundly Reduced CD1c+ Myeloid Dendritic Cell HLA-DR and CD86 Expression and Increased Tumor Necrosis Factor Production in Experimental Human Blood-Stage Malaria Infection.
Loughland JR, Minigo G, Burel J, Tipping PE, Piera KA, Amante FH, Engwerda CR, Good MF, Doolan DL, Anstey NM, McCarthy JS, Woodberry T. Loughland JR, et al. Infect Immun. 2016 Apr 22;84(5):1403-1412. doi: 10.1128/IAI.01522-15. Print 2016 May. Infect Immun. 2016. PMID: 26902728 Free PMC article.
Type I Interferons Regulate Immune Responses in Humans with Blood-Stage Plasmodium falciparum Infection.
Montes de Oca M, Kumar R, Rivera FL, Amante FH, Sheel M, Faleiro RJ, Bunn PT, Best SE, Beattie L, Ng SS, Edwards CL, Boyle GM, Price RN, Anstey NM, Loughland JR, Burel J, Doolan DL, Haque A, McCarthy JS, Engwerda CR. Montes de Oca M, et al. Among authors: loughland jr. Cell Rep. 2016 Oct 4;17(2):399-412. doi: 10.1016/j.celrep.2016.09.015. Cell Rep. 2016. PMID: 27705789 Free PMC article.
Early Immune Regulatory Changes in a Primary Controlled Human Plasmodium vivax Infection: CD1c+ Myeloid Dendritic Cell Maturation Arrest, Induction of the Kynurenine Pathway, and Regulatory T Cell Activation.
Woodberry T, Loughland JR, Minigo G, Burel JG, Amante FH, Piera KA, McNeil Y, Yeo TW, Good MF, Doolan DL, Engwerda CR, McCarthy JS, Anstey NM. Woodberry T, et al. Among authors: loughland jr. Infect Immun. 2017 May 23;85(6):e00986-16. doi: 10.1128/IAI.00986-16. Print 2017 Jun. Infect Immun. 2017. PMID: 28320838 Free PMC article.
Plasmacytoid dendritic cells appear inactive during sub-microscopic Plasmodium falciparum blood-stage infection, yet retain their ability to respond to TLR stimulation.
Loughland JR, Minigo G, Sarovich DS, Field M, Tipping PE, Montes de Oca M, Piera KA, Amante FH, Barber BE, Grigg MJ, William T, Good MF, Doolan DL, Engwerda CR, Anstey NM, McCarthy JS, Woodberry T. Loughland JR, et al. Sci Rep. 2017 Jun 1;7(1):2596. doi: 10.1038/s41598-017-02096-2. Sci Rep. 2017. PMID: 28572564 Free PMC article.
Loss of complement regulatory proteins on red blood cells in mild malarial anaemia and in Plasmodium falciparum induced blood-stage infection.
Oyong DA, Loughland JR, SheelaNair A, Andrew D, Rivera FDL, Piera KA, William T, Grigg MJ, Barber BE, Haque A, Engwerda CR, McCarthy JS, Anstey NM, Boyle MJ. Oyong DA, et al. Among authors: loughland jr. Malar J. 2019 Sep 18;18(1):312. doi: 10.1186/s12936-019-2962-0. Malar J. 2019. PMID: 31533836 Free PMC article.
The regulation of CD4+ T cells during malaria.
Kumar R, Loughland JR, Ng SS, Boyle MJ, Engwerda CR. Kumar R, et al. Among authors: loughland jr. Immunol Rev. 2020 Jan;293(1):70-87. doi: 10.1111/imr.12804. Epub 2019 Nov 1. Immunol Rev. 2020. PMID: 31674682 Review.
Transcriptional profiling and immunophenotyping show sustained activation of blood monocytes in subpatent Plasmodium falciparum infection.
Loughland JR, Woodberry T, Field M, Andrew DW, SheelaNair A, Dooley NL, Piera KA, Amante FH, Kenangalem E, Price RN, Engwerda CR, Anstey NM, McCarthy JS, Boyle MJ, Minigo G. Loughland JR, et al. Clin Transl Immunology. 2020 Jun 18;9(6):e1144. doi: 10.1002/cti2.1144. eCollection 2020. Clin Transl Immunology. 2020. PMID: 32566226 Free PMC article.
Th2-like T Follicular Helper Cells Promote Functional Antibody Production during Plasmodium falciparum Infection.
Chan JA, Loughland JR, de Labastida Rivera F, SheelaNair A, Andrew DW, Dooley NL, Wines BD, Amante FH, Webb L, Hogarth PM, McCarthy JS, Beeson JG, Engwerda CR, Boyle MJ. Chan JA, et al. Among authors: loughland jr. Cell Rep Med. 2020 Dec 22;1(9):100157. doi: 10.1016/j.xcrm.2020.100157. eCollection 2020 Dec 22. Cell Rep Med. 2020. PMID: 33377128 Free PMC article.
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