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Transposable elements and Alzheimer's disease pathogenesis.
Evering TH, Marston JL, Gan L, Nixon DF. Evering TH, et al. Among authors: gan l. Trends Neurosci. 2023 Mar;46(3):170-172. doi: 10.1016/j.tins.2022.12.003. Epub 2022 Dec 30. Trends Neurosci. 2023. PMID: 36588011 Free article.
Familial natural short sleep mutations reduce Alzheimer pathology in mice.
Dong Q, Gentry NW, McMahon T, Yamazaki M, Benitez-Rivera L, Wang T, Gan L, Ptáček L, Fu YH. Dong Q, et al. Among authors: gan l. iScience. 2022 Mar 15;25(4):103964. doi: 10.1016/j.isci.2022.103964. eCollection 2022 Apr 15. iScience. 2022. PMID: 35496999 Free PMC article.
Functional characterization of Alzheimer's disease genetic variants in microglia.
Yang X, Wen J, Yang H, Jones IR, Zhu X, Liu W, Li B, Clelland CD, Luo W, Wong MY, Ren X, Cui X, Song M, Liu H, Chen C, Eng N, Ravichandran M, Sun Y, Lee D, Van Buren E, Jiang MZ, Chan CSY, Ye CJ, Perera RM, Gan L, Li Y, Shen Y. Yang X, et al. Among authors: gan l. Nat Genet. 2023 Oct;55(10):1735-1744. doi: 10.1038/s41588-023-01506-8. Epub 2023 Sep 21. Nat Genet. 2023. PMID: 37735198 Free PMC article.
The AD odyssey 2023: Tales of single cell.
Luo W, Qu W, Gan L. Luo W, et al. Among authors: gan l. Cell. 2023 Sep 28;186(20):4257-4259. doi: 10.1016/j.cell.2023.09.001. Cell. 2023. PMID: 37774675
A global view of aging and Alzheimer's pathogenesis-associated cell population dynamics and molecular signatures in human and mouse brains.
Sziraki A, Lu Z, Lee J, Banyai G, Anderson S, Abdulraouf A, Metzner E, Liao A, Banfelder J, Epstein A, Schaefer C, Xu Z, Zhang Z, Gan L, Nelson PT, Zhou W, Cao J. Sziraki A, et al. Among authors: gan l. Nat Genet. 2023 Dec;55(12):2104-2116. doi: 10.1038/s41588-023-01572-y. Epub 2023 Nov 30. Nat Genet. 2023. PMID: 38036784 Free PMC article.
Microglial microRNAs mediate sex-specific responses to tau pathology.
Kodama L, Guzman E, Etchegaray JI, Li Y, Sayed FA, Zhou L, Zhou Y, Zhan L, Le D, Udeochu JC, Clelland CD, Cheng Z, Yu G, Li Q, Kosik KS, Gan L. Kodama L, et al. Among authors: gan l. Nat Neurosci. 2020 Feb;23(2):167-171. doi: 10.1038/s41593-019-0560-7. Epub 2019 Dec 23. Nat Neurosci. 2020. PMID: 31873194 Free PMC article.
Friend turned foe: TREM2 agonist in battles against tau.
Carling G, Luo W, Gan L. Carling G, et al. Among authors: gan l. J Exp Med. 2023 Jan 2;220(1):e20221850. doi: 10.1084/jem.20221850. Epub 2022 Nov 18. J Exp Med. 2023. PMID: 36399126 Free PMC article.
Tau activation of microglial cGAS-IFN reduces MEF2C-mediated cognitive resilience.
Udeochu JC, Amin S, Huang Y, Fan L, Torres ERS, Carling GK, Liu B, McGurran H, Coronas-Samano G, Kauwe G, Mousa GA, Wong MY, Ye P, Nagiri RK, Lo I, Holtzman J, Corona C, Yarahmady A, Gill MT, Raju RM, Mok SA, Gong S, Luo W, Zhao M, Tracy TE, Ratan RR, Tsai LH, Sinha SC, Gan L. Udeochu JC, et al. Among authors: gan l. Nat Neurosci. 2023 May;26(5):737-750. doi: 10.1038/s41593-023-01315-6. Epub 2023 Apr 24. Nat Neurosci. 2023. PMID: 37095396 Free PMC article.
DAP12 deficiency alters microglia-oligodendrocyte communication and enhances resilience against tau toxicity.
Chen H, Fan L, Guo Q, Wong MY, Yu F, Foxe N, Wang W, Nessim A, Carling G, Liu B, Lopez-Lee C, Huang Y, Amin S, Patel T, Mok SA, Song WM, Zhang B, Ma Q, Fu H, Gan L, Luo W. Chen H, et al. Among authors: gan l. bioRxiv [Preprint]. 2023 Oct 28:2023.10.26.563970. doi: 10.1101/2023.10.26.563970. bioRxiv. 2023. PMID: 37961594 Free PMC article. Preprint.
3,060 results