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Chemical Proteomics Reveals Antibiotic Targets of Oxadiazolones in MRSA.
Bakker AT, Kotsogianni I, Mirenda L, Straub VM, Avalos M, van den Berg RJBHN, Florea BI, van Wezel GP, Janssen APA, Martin NI, van der Stelt M. Bakker AT, et al. Among authors: florea bi. J Am Chem Soc. 2023 Jan 18;145(2):1136-1143. doi: 10.1021/jacs.2c10819. Epub 2022 Dec 30. J Am Chem Soc. 2023. PMID: 36584241 Free PMC article.
Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division.
Chang JT, Ciocca ML, Kinjyo I, Palanivel VR, McClurkin CE, Dejong CS, Mooney EC, Kim JS, Steinel NC, Oliaro J, Yin CC, Florea BI, Overkleeft HS, Berg LJ, Russell SM, Koretzky GA, Jordan MS, Reiner SL. Chang JT, et al. Among authors: florea bi. Immunity. 2011 Apr 22;34(4):492-504. doi: 10.1016/j.immuni.2011.03.017. Epub 2011 Apr 14. Immunity. 2011. PMID: 21497118 Free PMC article.
Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment.
Maynard CJ, Böttcher C, Ortega Z, Smith R, Florea BI, Díaz-Hernández M, Brundin P, Overkleeft HS, Li JY, Lucas JJ, Dantuma NP. Maynard CJ, et al. Among authors: florea bi. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13986-91. doi: 10.1073/pnas.0906463106. Epub 2009 Jul 30. Proc Natl Acad Sci U S A. 2009. PMID: 19666572 Free PMC article.
Novel activity-based probes for broad-spectrum profiling of retaining β-exoglucosidases in situ and in vivo.
Kallemeijn WW, Li KY, Witte MD, Marques AR, Aten J, Scheij S, Jiang J, Willems LI, Voorn-Brouwer TM, van Roomen CP, Ottenhoff R, Boot RG, van den Elst H, Walvoort MT, Florea BI, Codée JD, van der Marel GA, Aerts JM, Overkleeft HS. Kallemeijn WW, et al. Among authors: florea bi. Angew Chem Int Ed Engl. 2012 Dec 7;51(50):12529-33. doi: 10.1002/anie.201207771. Epub 2012 Nov 8. Angew Chem Int Ed Engl. 2012. PMID: 23139194
Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4.
Mari PO, Florea BI, Persengiev SP, Verkaik NS, Brüggenwirth HT, Modesti M, Giglia-Mari G, Bezstarosti K, Demmers JA, Luider TM, Houtsmuller AB, van Gent DC. Mari PO, et al. Among authors: florea bi. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18597-602. doi: 10.1073/pnas.0609061103. Epub 2006 Nov 21. Proc Natl Acad Sci U S A. 2006. PMID: 17124166 Free PMC article.
Incorporation of non-natural amino acids improves cell permeability and potency of specific inhibitors of proteasome trypsin-like sites.
Geurink PP, van der Linden WA, Mirabella AC, Gallastegui N, de Bruin G, Blom AE, Voges MJ, Mock ED, Florea BI, van der Marel GA, Driessen C, van der Stelt M, Groll M, Overkleeft HS, Kisselev AF. Geurink PP, et al. Among authors: florea bi. J Med Chem. 2013 Feb 14;56(3):1262-75. doi: 10.1021/jm3016987. Epub 2013 Jan 28. J Med Chem. 2013. PMID: 23320547 Free PMC article.
144 results